CAJ | 학술논문

“房颤促房颤”被认为是心房颤动的适应性改变。然而，心肌电生理是由其本身的结构特点决定以适应其功能的需要。心房有效不应期缩短是电重构的结果，虽可诱导快速频率，但更为重要的是恢复其生理功能的一种代偿机制：因各离子通道的作用并不相同，其变化需结合特定的时空背景。房颤结构重构是损伤效应的累积结果，其本质并非为促进房颤，而是损伤超越其代偿功能时的不可逆性改变，虽为一被动过程，但却直接影响相应心肌电生理功能。房颤的结构重构和电重构是相互促进的，心脏能否恢复窦性心律关键在于心房自身结构损伤的程度。
“방전촉방전”피인위시심방전동적괄응성개변。연이，심기전생리시유기본신적결구특점결정이괄응기공능적수요。심방유효불응기축단시전중구적결과，수가유도쾌속빈솔，단경위중요적시회복기생리공능적일충대상궤제：인각리자통도적작용병불상동，기변화수결합특정적시공배경。방전결구중구시손상효응적루적결과，기본질병비위촉진방전，이시손상초월기대상공능시적불가역성개변，수위일피동과정，단각직접영향상응심기전생리공능。방전적결구중구화전중구시상호촉진적，심장능부회복두성심률관건재우심방자신결구손상적정도。
"Atrial fibrillation (AF ) begets AF" is taken as to be adaptive change for AF . However , cardiac electrophysiology is decided by its own structure characteristics to meet the need of its function .In AF ,shortening of atrial effective refractory period (AERP) is the result of the electrical remodeling ,which could induce rapid arrhythmia . But first of all ,it is a kind of compensatory mechanism to recover its function .The role of each ion channel in atrial cardiac muscle cells is different ,and its change should be combined with the specific background of time and space .The structure remodeling of AF is the cumulative result from damage effect ,as a passive process ,its essence in that the damage beyond its compensatory function causing irreversible change and directly affect the electrophysiological function of corresponding myocardial .Electrical remodeling and structural remodeling begets each other ,restoring sinus rhythm is decided by atrial structure .