CAJ | 학술논문

目的：分析和研究治疗子宫内膜异位症使用米非司酮进行治疗的临床效果及其安全性。方法收集子宫内膜异位症患者共80例，所有患者均在月经来潮后第1d左右的时间内进行米非司酮的口服，剂量为10mg/d，疗程为3个月。在治疗完成后对患者治疗前后症状的改善、体征的改善、不良反应等进行调查和统计。结果治疗3个月后，患者的主观症状评分与治疗前相比显著下降，子宫内膜组织当中的血管内皮生长因子、增殖细胞核抗原和微血管密度表达量与治疗前相比明显下降，均<0.05。结论在治疗子宫内膜异位症时使用米非司酮，治疗的效果较好，能够有效抑制子宫内膜的增殖及其新生血管的形成。
목적：분석화연구치료자궁내막이위증사용미비사동진행치료적림상효과급기안전성。방법수집자궁내막이위증환자공80례，소유환자균재월경래조후제1d좌우적시간내진행미비사동적구복，제량위10mg/d，료정위3개월。재치료완성후대환자치료전후증상적개선、체정적개선、불량반응등진행조사화통계。결과치료3개월후，환자적주관증상평분여치료전상비현저하강，자궁내막조직당중적혈관내피생장인자、증식세포핵항원화미혈관밀도표체량여치료전상비명현하강，균<0.05。결론재치료자궁내막이위증시사용미비사동，치료적효과교호，능구유효억제자궁내막적증식급기신생혈관적형성。
Objective To analyze and study the treatment of endometriosis using mifepristone for treatment of clinical ef ect and safety.Methods A total of endometriosis patients with 80 cases,al patients underwent oral mifepristone within four days after menstruation time around, the daily dose of 10mg,treatment for two months.After completion of treatment for patients before and and statistics. Results After two months, before the patient's subjective symptom scores decreased significantly compared <0.05.Conclusion In the treatment of endometriosis non meters mifepristone, bet er treatment ef ect,can ef ectively inhibit the formation of endometrial cel proliferation and angiogenesis.