CAJ | 학술논문

目的探讨2型糖尿病患者尿微量白蛋白( UMA)与颈动脉内中膜厚度( IMT)的关系,研究微量白蛋白尿在2型糖尿病患者中预测大血管病变的价值。方法选取尿微量白蛋白异常的2型糖尿病患者111例,根据尿微量蛋白水平分为尿蛋白正常组64例(尿微量白蛋白<30mg/L),微量蛋白尿阳性组47例(尿微量白蛋白>30mg/L)。微量尿蛋白组又分为3个亚组,即A组19例(尿微量白蛋白30~50mg/L),B组14例(尿微量白蛋白50~100mg/L),C组14例(尿微量白蛋白100~300mg/L)。比较各组及各亚组微量尿蛋白水平及颈动脉内中膜厚度,探讨其相关关系。结果UMA与IMT呈正相关性,尿微量白蛋白高即颈动脉内中膜厚度高。结论尿微量白蛋白与颈动脉硬化相关,尿微量白蛋白越高,与颈动脉硬化相关性越密切。尿微量白蛋白可能为2型糖尿病大血管及微血管病变的标志物。
목적탐토2형당뇨병환자뇨미량백단백( UMA)여경동맥내중막후도( IMT)적관계,연구미량백단백뇨재2형당뇨병환자중예측대혈관병변적개치。방법선취뇨미량백단백이상적2형당뇨병환자111례,근거뇨미량단백수평분위뇨단백정상조64례(뇨미량백단백<30mg/L),미량단백뇨양성조47례(뇨미량백단백>30mg/L)。미량뇨단백조우분위3개아조,즉A조19례(뇨미량백단백30~50mg/L),B조14례(뇨미량백단백50~100mg/L),C조14례(뇨미량백단백100~300mg/L)。비교각조급각아조미량뇨단백수평급경동맥내중막후도,탐토기상관관계。결과UMA여IMT정정상관성,뇨미량백단백고즉경동맥내중막후도고。결론뇨미량백단백여경동맥경화상관,뇨미량백단백월고,여경동맥경화상관성월밀절。뇨미량백단백가능위2형당뇨병대혈관급미혈관병변적표지물。
Objective Research on the relationship between microalbuminuria and carotid intima-media thickness in type 2 diabetic patient,Prediction of major vascular lesions of urinary albumin in type 2 diabetes mellituspatients value. Method Based on patients with type 2 diabetes in 111 cases. According to the microalbuminuria levels were divided into normal group 64 cases(microalbuminuria<30mg/L)and 47 cases of microalbuminuria group(microalbuminuria>30mg/L). Mi-croalbuminuria group was divided into 3 sub groups,namely group A 19 cases(microalbuminuria 30-50mg/L),14 cases in B group(microalbuminuria 50-100mg/L),group C 14 cases with microalbuminuria 100-300mg/L). Comparison of groups and subgroups of microalbuminuria and carotid artery intima-media thickness, and explore its correlation. Result Mi-croalbuminuria and carotid artery intima-media thickness process positive correlation. Conclusion Microalbuminuria may be the marker of macrovascular and microvessels disease in type2 diabetes mellitus.