CAJ | 학술논문

低剂量CT肺癌筛查检出肺癌的影像特征
저제량CT폐암사사검출폐암적영상특정
Imaging characteristics of lung cancer detected by low-dose CT lung cancer screening

万方数据

中华放射学杂志中華放射學雜誌 중화방사학잡지
Chinese Journal of Radiology
2015年 5期 336-339 ,共4页

王建卫%吴宁%唐威%黄遥%赵世俊%李蒙%周丽娜%王玉婕%陆雯雯%刘士远

왕건위%오저%당위%황요%조세준%리몽%주려나%왕옥첩%륙문문%류사원

肺肿瘤%体层摄影术,X线计算机%辐射剂量肺腫瘤%體層攝影術,X線計算機%輻射劑量
폐종류%체층섭영술,X선계산궤%복사제량
Lung neoplasms%Tomography,X-ray computed%Radiation dosage

目的分析低剂量CT（LDCT）筛查检出肺癌的影像特征。方法回顾性分析2007年7月1日至2013年6月30日接受LDCT筛查受检者7141例，其中男4710例、女2431例，年龄40~88岁，中位年龄47岁，行9721次LDCT检查。≤39岁自愿参加筛查者1071例。对手术和病理证实的肺癌进行影像学分析，根据肺内病变是否含有磨玻璃密度影（GGO）、是否能够完全遮盖肺实质，将病变分为实性、部分实性和非实性3类。结果 LDCT检出肺癌患者31例，检出率为0.4%；32个癌灶中腺癌30个、类癌和小细胞肺癌各1个。31个非小细胞肺癌病灶中，实性结节共18个，其中实性结节经典型14个、不规则型2个、不典型结节型2个；部分实性结节12个，其中部分实性结节型8个、不规则型2个、囊腔型2个；非实性型1个。LDCT诊断肺癌或肺癌可能性大24个（77.4%）、不能定性或定性困难3个（9.7%）、诊断良性或良性可能大3个（9.7%）、基线筛查漏诊1个（3.1%）。结论 LDCT筛查检出的肺癌影像表现多样，可为LDCT肺癌筛查提供借鉴。
목적분석저제량CT（LDCT）사사검출폐암적영상특정。방법회고성분석2007년7월1일지2013년6월30일접수LDCT사사수검자7141례，기중남4710례、녀2431례，년령40~88세，중위년령47세，행9721차LDCT검사。≤39세자원삼가사사자1071례。대수술화병리증실적폐암진행영상학분석，근거폐내병변시부함유마파리밀도영（GGO）、시부능구완전차개폐실질，장병변분위실성、부분실성화비실성3류。결과 LDCT검출폐암환자31례，검출솔위0.4%；32개암조중선암30개、유암화소세포폐암각1개。31개비소세포폐암병조중，실성결절공18개，기중실성결절경전형14개、불규칙형2개、불전형결절형2개；부분실성결절12개，기중부분실성결절형8개、불규칙형2개、낭강형2개；비실성형1개。LDCT진단폐암혹폐암가능성대24개（77.4%）、불능정성혹정성곤난3개（9.7%）、진단량성혹량성가능대3개（9.7%）、기선사사루진1개（3.1%）。결론 LDCT사사검출적폐암영상표현다양，가위LDCT폐암사사제공차감。
Objective To analyze the imaging characteristics of lung cancer detected by LDCT ( low-dose CT )lung cancer screening. Methods Between July 1st, 2007 and June 30th, 2013, 7 141 asymptomatic enrolled participants aged 40-88 years old (male 4 710, female 2 431, median age 47), and 1 071 volunteer participants aged ≤39 underwent chest LDCT. The imaging characteristics were analyzed retrospectively in lung cancer pathologically proved. Three types were classified according to the imaging findings: solid lesion, part-solid lesion and non-solid lesion. Results A total of 31 participants (32 lesions) were diagnosed as lung cancer, including 30 adenocarcinomas, 1 carcinoid and 1 small cell lung cancer. The detecting rate of the lung cancer was 0.4%(31/8 212). The solid lesion was further classified as classical solid nodule, irregular solid lesion and atypical solid nodule, and the part-solid lesion was further classified as part-solid nodule, irregular part-solid lesion and cystic part-solid nodule. Lung cancer or probably lung cancer was diagnosed in 24 cases (77.4%), and uncertainty diagnosis was made in 3 cases (9.7%). Benign or probably benign was diagnosed in 3 cases, and another 1 cases were missed at baseline screening. The false positive rate and the false negative rate was 9.7%and 3.1%, respectively. Conclusion The imaging characteristics of lung cancer detected by LDCT are varied, which provide preliminary experience in lung cancer screening.