CAJ | 학술논문

目的探讨原发性腹膜后神经鞘瘤的手术治疗效果、预后及复发的影响因素.方法回顾性分析1993年1月至2012年12月解放军总医院普通外科收治的109例原发性腹膜后神经鞘瘤患者临床资料.结果原发性腹膜后良性神经鞘瘤患者,1、3、5年总生存率均为100％,统计结果证明:肿瘤直径、手术根治度与复发相关.原发性腹膜后恶性神经鞘瘤患者,1、3、5年总生存率分别为89.6％、62.1％、41.4％,复发率分别为41.4％、65.5％、72.4％.肿瘤直径、手术根治度、肿瘤级别与预后相关,其中肿瘤级别与复发相关,也是预后的独立影响因素.结论根治性手术是原发性腹膜后神经鞘瘤的主要治疗方式,良性神经鞘瘤患者预后较好,肿瘤直径、手术根治度与复发相关.恶性神经鞘瘤患者预后与肿瘤直径、手术根治度、肿瘤级别相关,其中肿瘤级别与复发相关,也是预后的独立影响因素.
목적 탐토원발성복막후신경초류적수술치료효과、예후급복발적영향인소.방법 회고성분석1993년1월지2012년12월해방군총의원보통외과수치적109례원발성복막후신경초류환자림상자료.결과 원발성복막후량성신경초류환자,1、3、5년총생존솔균위100％,통계결과증명:종류직경、수술근치도여복발상관.원발성복막후악성신경초류환자,1、3、5년총생존솔분별위89.6％、62.1％、41.4％,복발솔분별위41.4％、65.5％、72.4％.종류직경、수술근치도、종류급별여예후상관,기중종류급별여복발상관,야시예후적독립영향인소.결론 근치성수술시원발성복막후신경초류적주요치료방식,량성신경초류환자예후교호,종류직경、수술근치도여복발상관.악성신경초류환자예후여종류직경、수술근치도、종류급별상관,기중종류급별여복발상관,야시예후적독립영향인소.
Objective To evaluate the surgical efficacies of primary retroperitoneal schwannoma (PRS) and analyze its risk factors for survival and recurrence.Methods From January 1993 to December 2012,109 patients diagnosed with primary retroperitoneal schwannoma were treated at our department.And their clinical data were retrospectively analyzed.Results The overall 1,3,5-year survival rates of benign PRS were all 100％.Univariate analyses revealed that tumor size and modus operandi of tumor resection were associated with recurrence rate.For malignant PRS,the overall 1,3,5-year survival and recurrence rates were 89.6％,62.1％,41.4％ and 41.4％,65.5％,72.4％ respectively.Univariate analyses revealed that tumor size,modus operandi of tumor resection and tumor grade were associated with survival rate.Tumor grade was associated with recurrence rate and it was also an independent prognostic factor.Conclusion The major management of PRS is complete excision.Benign PRS has an excellent survival rate.And tumor size and modus operandi of tumor resection are associated with recurrence rate.The survival rate of malignant PRS is associated with tumor size,modus operandi of tumor resection and tumor grade.As an independent prognostic factor,tumor grade is associated with recurrence rate.