新疆医科大学学报
新疆醫科大學學報
신강의과대학학보
JOURNAL OF XINJIANG MEDICAL UNIVERSITY
2015年
6期
739-741,744
,共4页
陈慕芝%巴哈尔古丽·力提甫%照日格图
陳慕芝%巴哈爾古麗·力提甫%照日格圖
진모지%파합이고려·력제보%조일격도
结缔组织病%甲状腺疾病%甲状腺功能
結締組織病%甲狀腺疾病%甲狀腺功能
결체조직병%갑상선질병%갑상선공능
connective tissue disease%thyroid disease%thyroid function
目的：探讨结缔组织病（CTD）与甲状腺疾病的相关性。方法选取2013年9月－2014年9月在新疆医科大学附属中医医院风湿科住院并接受甲状腺疾病相关检查的55例结缔组织病患者（CTD 组）为研究对象，选取30例健康体检者作为对照组，比较两组人群伴发甲状腺疾病的患病率，同时分析不同甲状腺疾病在不同类型CTD 中的患病率。结果CTD 组患者中伴甲状腺疾病者21例（38．18％），对照组伴甲状腺疾病者2例（6．67％），两组比较差异有统计学意义（P ＞0．05）；CTD 合并甲状腺疾病患者中，亚临床甲状腺功能减退症（42．86％）最常见，其次为桥本氏甲状腺炎（28．57％）；合并甲状腺疾病的 CTD 患者，各构成比依次为：系统性红斑狼疮47．06％、干燥综合征44．00％、混合性结缔组织病25．00％、系统性硬化症14．29％；CTD 患者中伴／不伴甲状腺疾病者血清中血沉、C 反应蛋白及补体 C3比较差异无统计学意义（P ＞0．05）。结论CTD 患者易伴发甲状腺疾病，二者有较强的相关性，有无甲状腺疾病与 CTD 的病情活动度无关。
目的：探討結締組織病（CTD）與甲狀腺疾病的相關性。方法選取2013年9月－2014年9月在新疆醫科大學附屬中醫醫院風濕科住院併接受甲狀腺疾病相關檢查的55例結締組織病患者（CTD 組）為研究對象，選取30例健康體檢者作為對照組，比較兩組人群伴髮甲狀腺疾病的患病率，同時分析不同甲狀腺疾病在不同類型CTD 中的患病率。結果CTD 組患者中伴甲狀腺疾病者21例（38．18％），對照組伴甲狀腺疾病者2例（6．67％），兩組比較差異有統計學意義（P ＞0．05）；CTD 閤併甲狀腺疾病患者中，亞臨床甲狀腺功能減退癥（42．86％）最常見，其次為橋本氏甲狀腺炎（28．57％）；閤併甲狀腺疾病的 CTD 患者，各構成比依次為：繫統性紅斑狼瘡47．06％、榦燥綜閤徵44．00％、混閤性結締組織病25．00％、繫統性硬化癥14．29％；CTD 患者中伴／不伴甲狀腺疾病者血清中血沉、C 反應蛋白及補體 C3比較差異無統計學意義（P ＞0．05）。結論CTD 患者易伴髮甲狀腺疾病，二者有較彊的相關性，有無甲狀腺疾病與 CTD 的病情活動度無關。
목적：탐토결체조직병（CTD）여갑상선질병적상관성。방법선취2013년9월－2014년9월재신강의과대학부속중의의원풍습과주원병접수갑상선질병상관검사적55례결체조직병환자（CTD 조）위연구대상，선취30례건강체검자작위대조조，비교량조인군반발갑상선질병적환병솔，동시분석불동갑상선질병재불동류형CTD 중적환병솔。결과CTD 조환자중반갑상선질병자21례（38．18％），대조조반갑상선질병자2례（6．67％），량조비교차이유통계학의의（P ＞0．05）；CTD 합병갑상선질병환자중，아림상갑상선공능감퇴증（42．86％）최상견，기차위교본씨갑상선염（28．57％）；합병갑상선질병적 CTD 환자，각구성비의차위：계통성홍반랑창47．06％、간조종합정44．00％、혼합성결체조직병25．00％、계통성경화증14．29％；CTD 환자중반／불반갑상선질병자혈청중혈침、C 반응단백급보체 C3비교차이무통계학의의（P ＞0．05）。결론CTD 환자역반발갑상선질병，이자유교강적상관성，유무갑상선질병여 CTD 적병정활동도무관。
Objective To investigate the correlation between connective tissue diseases and thyroid diseases. Methods 55 in-patients with connective tissue diseases by thyroid function tests in 2013.9-2014.9 in the Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University were selected as the re-search group and 30 healthy people were taken as the control group simultaneously.The prevalence of TD between the research group and control group was compared,and the analysis on the prevalence of differ-ent thyroid diseases in patients with different connective tissue diseases was conducted.Results 21 cases in the research group were found thyroid diseases (38.18%),2 cases in the control group were found thyroid disease (6.67%),with significant difference in two groups (P >0.05);The subclinical hypothyroidism is the most common(42.86%)in the patients with connective tissue diseases associated with thyroid disease, followed by Hashimoto′s thyroiditis (28.57%);The incidence of connective tissue diseases associated with thyroid disease was 47.06% in SLE,44% in SS,25% in MCTD,14.29% in SSc;There was no significant difference between the research group of connective tissue disease associated with/without thyroid disease in ESR,CRP and C3 (P >0.05).Conclusion The strong correlation between connective tissue disease and thyroid diseases was found.Thyroid diseases was found unrelated with the activity of connective tissue diseases.
