医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2015年
11期
1419-1420
,共2页
肾透析%中心静脉留置导管%感染
腎透析%中心靜脈留置導管%感染
신투석%중심정맥류치도관%감염
Renal dialysis%Central venous catheter%Infection
目的：分析血液透析（HD）患者带涤纶环中心静脉留置导管相关血流感染（CRBSI）的危险因素。方法：对我科带涤纶环中心静脉留置导管的患者进行了前瞻性研究。导管插入后及插入后1个月记录实验室和临床变量，取平均值分析，临床过程跟踪到满2年，导管失败或C RBS I被记录为终点事件，期间根据患者是否C RBS I分为感染组或非感染组。结果：CRBSI组患者C‐反应蛋白（CRP）、年龄、低密度脂蛋白（LDL）显著高于非感染组；而血白蛋白（Alb）、标准化蛋白分解率（nPCR）低于非感染组。患者CRBSI的危险因素为：CRP、nPCR、糖尿病。结论：营养状况、微炎症状态、血脂与HD带涤纶环中心静脉留置导管CRBSI有关，CRP、nPCR、糖尿病是CRBSI的危险因素。
目的：分析血液透析（HD）患者帶滌綸環中心靜脈留置導管相關血流感染（CRBSI）的危險因素。方法：對我科帶滌綸環中心靜脈留置導管的患者進行瞭前瞻性研究。導管插入後及插入後1箇月記錄實驗室和臨床變量，取平均值分析，臨床過程跟蹤到滿2年，導管失敗或C RBS I被記錄為終點事件，期間根據患者是否C RBS I分為感染組或非感染組。結果：CRBSI組患者C‐反應蛋白（CRP）、年齡、低密度脂蛋白（LDL）顯著高于非感染組；而血白蛋白（Alb）、標準化蛋白分解率（nPCR）低于非感染組。患者CRBSI的危險因素為：CRP、nPCR、糖尿病。結論：營養狀況、微炎癥狀態、血脂與HD帶滌綸環中心靜脈留置導管CRBSI有關，CRP、nPCR、糖尿病是CRBSI的危險因素。
목적：분석혈액투석（HD）환자대조륜배중심정맥류치도관상관혈류감염（CRBSI）적위험인소。방법：대아과대조륜배중심정맥류치도관적환자진행료전첨성연구。도관삽입후급삽입후1개월기록실험실화림상변량，취평균치분석，림상과정근종도만2년，도관실패혹C RBS I피기록위종점사건，기간근거환자시부C RBS I분위감염조혹비감염조。결과：CRBSI조환자C‐반응단백（CRP）、년령、저밀도지단백（LDL）현저고우비감염조；이혈백단백（Alb）、표준화단백분해솔（nPCR）저우비감염조。환자CRBSI적위험인소위：CRP、nPCR、당뇨병。결론：영양상황、미염증상태、혈지여HD대조륜배중심정맥류치도관CRBSI유관，CRP、nPCR、당뇨병시CRBSI적위험인소。
Objective :To analyse the risk factors of dialysis cuff central venous catheter‐related bloodstream infections (CRBSI) .Methods :This was a prospective study ,Hemodialysis (HD) patients with cuff central venous cathetes was studied .After catheterization and one month later ,Laboratory and clinical variables was recorded .Took the mean value analysis ,The clinical course of tracking to 2 years ,endpoint events was recorded as catheter failure or CRBSI .All pa‐tients were divided into CRBSI and no CRBSI .Results:The serum C‐reactive protein (CRP) ,age ,low density lipopro‐tein (LDL) in HD with CRBSI were significantly higher than those without CRBSI patients .But the serum albumin (Alb) and normalized protein catabolic rate (nPCR) were significantly decreased .The risk factors of HD patients with CRBSI were CRP ,nPCR and primary diabetes .Conclusion:There were relationship between nutritional status ,micro‐in‐flammation ,blood lipids and CRBSI in HD with cuff central venous catheter patients ,CRP ,nPCR ,diabetes is a risk fac‐tor of HD patients with CRBSI .
