CAJ | 학술논문

目的：探讨齐拉西酮联合脑电生物反馈治疗对慢性精神分裂症患者社会功能康复的影响。方法：将110例慢性精神分裂症患者随机分为齐拉西酮联合脑电生物反馈组55例（研究组，实际完成53例）和齐拉西酮组55例（对照组，实际完成52例），分别予齐拉西酮联合脑电生物反馈和齐拉西酮治疗8周。采用简明精神病量表（BPRS ）、住院精神病患者社会功能评定量表（SSPI）评定。结果：第8周末研究组的BPRS总分的减分和BPRS减分率的增分较对照组显著（ t1＝－3．38，P＜0．01；t2＝2．54，P＜0．05）；研究组的显效率（64．15％）与对照组（42．31％）比较，差异有统计学意义（χ2＝5．571，P＝0．018）。研究组SSPI总分及各因子（除外日常生活能力）得分显著高于对照组（P＜0．01或P＜0.05）。结论：齐拉西酮联合脑电生物反馈治疗对慢性精神分裂症的疗效及社会功能缺陷的改善优于单用齐拉西酮。
목적：탐토제랍서동연합뇌전생물반궤치료대만성정신분렬증환자사회공능강복적영향。방법：장110례만성정신분렬증환자수궤분위제랍서동연합뇌전생물반궤조55례（연구조，실제완성53례）화제랍서동조55례（대조조，실제완성52례），분별여제랍서동연합뇌전생물반궤화제랍서동치료8주。채용간명정신병량표（BPRS ）、주원정신병환자사회공능평정량표（SSPI）평정。결과：제8주말연구조적BPRS총분적감분화BPRS감분솔적증분교대조조현저（ t1＝－3．38，P＜0．01；t2＝2．54，P＜0．05）；연구조적현효솔（64．15％）여대조조（42．31％）비교，차이유통계학의의（χ2＝5．571，P＝0．018）。연구조SSPI총분급각인자（제외일상생활능력）득분현저고우대조조（P＜0．01혹P＜0.05）。결론：제랍서동연합뇌전생물반궤치료대만성정신분렬증적료효급사회공능결함적개선우우단용제랍서동。
Objective :To explore Ziprasidone joint EEG biofeedback treatment of chronic schizophrenia and its impact on the social function of the rehabilitation of patients .Methods :110 patients with chronic schizophrenia were randomly divided into Ziprasidone combined EEG biofeedback group 55 cases (53 cases actually completed ) and Ziprasidone group of 55 cases (52 cases actually completed) ,Respectively to give Ziprasidone combined with EEG biofeedback and Ziprasidone treatment lasted eight weeks .Using Brief Psychiatric Rating Scale (BPRS) ,the social function of psychiat‐ric inpatients Rating Scale (SSPI) were evaluated .Results:8th week ,the reduction rate of the study group of BPRS total score minus points and increase BPRS scores were higher ,statistically significant (t1 = -3 .38 ,P<0 .01 ;t2 =2 .54 ,P<0 .05);study group effective rate 64 .15% and 42 .31% in the control group was statistically significant difference(χ2 =5 .571 ,P=0 .018) .SSPI scores and factor scores (except for activities of daily living ) of study group growth points were higher ,statistically significant (P<0 .01 or P<0 .05) .Conclusion:Ziprasidone joint EEG biofeedback therapy to improve the efficacy of chronic schizophrenia and social dysfunction is better than a single treatment with Ziprasidone .