医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
10期
1783-1785
,共3页
邱俊霖%钟宇华%梁华晟%曾云先
邱俊霖%鐘宇華%樑華晟%曾雲先
구준림%종우화%량화성%증운선
糖尿病%结肠癌%胰岛素样生长因子%晚期糖基化产物受体
糖尿病%結腸癌%胰島素樣生長因子%晚期糖基化產物受體
당뇨병%결장암%이도소양생장인자%만기당기화산물수체
Diabetes mellitus%Colorectal cancer%Insulin-like growth factor%Receptor for advanced glycation end products
糖尿病与结肠癌的关系被越来越多的研究所证实。糖尿病患者容易引起结肠癌,且其治疗效果和预后比单纯结肠癌差。为了预防和治疗糖尿病合并结肠癌,很多研究关注糖尿病与结肠癌的关系。一些研究认为,胰岛素及胰岛素样生长因子1、晚期糖基化产物受体及其配体是重要的机制。在细胞、动物、人体标本的研究中,越来越多的证据支持这些因素与糖尿病及结肠癌的关联有关。该文就糖尿病与结肠癌关系的研究进展予以综述。
糖尿病與結腸癌的關繫被越來越多的研究所證實。糖尿病患者容易引起結腸癌,且其治療效果和預後比單純結腸癌差。為瞭預防和治療糖尿病閤併結腸癌,很多研究關註糖尿病與結腸癌的關繫。一些研究認為,胰島素及胰島素樣生長因子1、晚期糖基化產物受體及其配體是重要的機製。在細胞、動物、人體標本的研究中,越來越多的證據支持這些因素與糖尿病及結腸癌的關聯有關。該文就糖尿病與結腸癌關繫的研究進展予以綜述。
당뇨병여결장암적관계피월래월다적연구소증실。당뇨병환자용역인기결장암,차기치료효과화예후비단순결장암차。위료예방화치료당뇨병합병결장암,흔다연구관주당뇨병여결장암적관계。일사연구인위,이도소급이도소양생장인자1、만기당기화산물수체급기배체시중요적궤제。재세포、동물、인체표본적연구중,월래월다적증거지지저사인소여당뇨병급결장암적관련유관。해문취당뇨병여결장암관계적연구진전여이종술。
More and more researches have proved the relationship between diabetes and colon cancer. Diabetics are more prone to develop colon cancer,and simple colon cancer has a better therapeutic effect and prognosis than the colon cancer with diabetes.For the prevention and treatment of colon cancer,many reports are focused on how diabetes mellitus affect colon cancer,and some reports believe insulin and insulin like factor-1,advanced glycosylation product receptor and its ligand are important mechanisms.In the study of cells,animal and human specimens,more and more evidences support the association between diabetes and colon cancer,and here is to make a review of the research progress.