中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
6期
1056-1059,1060
,共5页
锡类散%质量标准%薄层色谱法%高效液相色谱法%气相色谱法
錫類散%質量標準%薄層色譜法%高效液相色譜法%氣相色譜法
석류산%질량표준%박층색보법%고효액상색보법%기상색보법
Xilei San%Quality standard%TLC%HPLC%GC
目的：：对锡类散质量标准进行研究。方法：采用薄层色谱法对青黛和牛黄进行定性鉴别,采用高效液相色谱法对青黛和牛黄进行含量测定,采用气相色谱法对冰片进行含量测定。结果：靛玉红进样量在0.043~4.255μg范围内与其峰面积呈良好的线性关系(r=0.9992),平均回收率为97.9%,RSD=1.5%(n=6)；胆红素对照品进样量在9.968×10-4~9.968×10-2μg范围内与其峰面积呈良好的线性关系(r =0.9999),平均回收率为95.3%,RSD =0.55%(n =6)；冰片进样量在0.0103~0.8266 mg范围内与其峰面积呈良好的线性关系(r=0.9998),平均回收率为94.9%,RSD=3.2%(n=6)。结论：该方法准确,专属性好,能有效控制锡类散的质量。
目的：：對錫類散質量標準進行研究。方法：採用薄層色譜法對青黛和牛黃進行定性鑒彆,採用高效液相色譜法對青黛和牛黃進行含量測定,採用氣相色譜法對冰片進行含量測定。結果：靛玉紅進樣量在0.043~4.255μg範圍內與其峰麵積呈良好的線性關繫(r=0.9992),平均迴收率為97.9%,RSD=1.5%(n=6)；膽紅素對照品進樣量在9.968×10-4~9.968×10-2μg範圍內與其峰麵積呈良好的線性關繫(r =0.9999),平均迴收率為95.3%,RSD =0.55%(n =6)；冰片進樣量在0.0103~0.8266 mg範圍內與其峰麵積呈良好的線性關繫(r=0.9998),平均迴收率為94.9%,RSD=3.2%(n=6)。結論：該方法準確,專屬性好,能有效控製錫類散的質量。
목적：：대석류산질량표준진행연구。방법：채용박층색보법대청대화우황진행정성감별,채용고효액상색보법대청대화우황진행함량측정,채용기상색보법대빙편진행함량측정。결과：전옥홍진양량재0.043~4.255μg범위내여기봉면적정량호적선성관계(r=0.9992),평균회수솔위97.9%,RSD=1.5%(n=6)；담홍소대조품진양량재9.968×10-4~9.968×10-2μg범위내여기봉면적정량호적선성관계(r =0.9999),평균회수솔위95.3%,RSD =0.55%(n =6)；빙편진양량재0.0103~0.8266 mg범위내여기봉면적정량호적선성관계(r=0.9998),평균회수솔위94.9%,RSD=3.2%(n=6)。결론：해방법준학,전속성호,능유효공제석류산적질량。
Objective:To research the quality standard for Xilei San. Methods:Imdigo naturalis and calculus bovis were identi-fied by TLC and their contents were determined by HPLC, and Borneolum syntheticum was determined by GC. Results: Indirubin showed good linearity over the concentration range of 0. 043-4. 255 0 μg(r=0. 999 2) with the average recovery of 97. 9%(RSD=1.5%,n=6). Bilirubin showed good linearity over the concentration range of 9.968 ×10 -4-9.968 ×10 -2 μg(r=0.999 9) with the average recovery of 95.3%(RSD =0.55%, n =6). Borneolum syntheticum showed good linearity over the concentration range of 0. 010 3-0. 826 6 mg(r=0. 999 8) with the average recovery of 94. 9%(RSD=3. 2%,n=6). Conclusion: The method is accurate with good reproducibility,which can be used as the quality control for Xilei San.
