CAJ | 학술논문

目的：比较腰-硬联合麻醉与全身麻醉对麻黄碱升压反应的影响。方法：手术治疗患者74例，随机将其分为对照组与观察组，各37例。对照组采用腰-硬联合麻醉，观察组给予全麻，两组术中均给予麻黄碱。比较用药后两组舒张压与收缩压水平。结果：观察组在 T1～T5时间点舒张压均显著高于 T0，亦明显高于对照组(P＜0.05)。观察组在T2～T5时间点收缩压均显著高于T0，且T5时收缩压显著高于对照组(P＜0.05)。结论：临床手术中应用麻黄碱可显著抑制低血压的发生，而全麻手术中麻黄碱升压反应明显好于腰-硬联合麻醉，具有更为满意的临床安全性。
목적：비교요-경연합마취여전신마취대마황감승압반응적영향。방법：수술치료환자74례，수궤장기분위대조조여관찰조，각37례。대조조채용요-경연합마취，관찰조급여전마，량조술중균급여마황감。비교용약후량조서장압여수축압수평。결과：관찰조재 T1～T5시간점서장압균현저고우 T0，역명현고우대조조(P＜0.05)。관찰조재T2～T5시간점수축압균현저고우T0，차T5시수축압현저고우대조조(P＜0.05)。결론：림상수술중응용마황감가현저억제저혈압적발생，이전마수술중마황감승압반응명현호우요-경연합마취，구유경위만의적림상안전성。
Objective:To compare the influence of combined spinal-epidural anesthesia with general anesthesia on pressor effects of ephedrine.Methods:74 cases of patients with surgical treatment were randomly divided into the control group and the observation group,with 37 cases in each group.The control group were given combined spinal-epidural anesthesia,while the observation group were given general anesthesia,and the two group were given ephedrine in operation.After the medicine,the diastolic blood pressure levels and systolic blood pressure levels of the two groups were compared.Results:The diastolic blood pressure of the observation group in time points of T1~T5 were significantly higher than that of T0,which was also significantly higher than that of the control group(P<0.05).The systolic blood pressure of the observation group in time points of T2~T5 were significantly higher than that of T0 and the systolic blood pressure of T5 was significantly higher than that of the control group(P<0.05).Conclusion:The application of ephedrine in clinical operation could inhibit the occurrence of hypotension significantly,while the pressor effects of ephedrine in general anesthesia surgery was much better than that of the combined spinal-epidural anesthesia and had more satisfactory clinical safety.