中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
6期
1014-1016
,共3页
壳聚糖%聚乙二醇%研究进展
殼聚糖%聚乙二醇%研究進展
각취당%취을이순%연구진전
Chitosan%Polyethylene glycol%Research progress
目的：：为聚乙二醇修饰壳聚糖的深入研究提供参考。方法：通过查阅、检索2004~2014年国内外相关文献及资料，并进行总结归纳。结果：聚乙二醇修饰壳聚糖的方法多样，可应用于制备纳米药物载体、制备基因治疗的载体、温敏性水凝胶、高分子前药以及组织工程修复材料。结论：聚乙二醇修饰的壳聚糖在生物医药领域研究广泛，但相关研究仅限于体外，体内研究需进一步系统和深入。
目的：：為聚乙二醇脩飾殼聚糖的深入研究提供參攷。方法：通過查閱、檢索2004~2014年國內外相關文獻及資料，併進行總結歸納。結果：聚乙二醇脩飾殼聚糖的方法多樣，可應用于製備納米藥物載體、製備基因治療的載體、溫敏性水凝膠、高分子前藥以及組織工程脩複材料。結論：聚乙二醇脩飾的殼聚糖在生物醫藥領域研究廣汎，但相關研究僅限于體外，體內研究需進一步繫統和深入。
목적：：위취을이순수식각취당적심입연구제공삼고。방법：통과사열、검색2004~2014년국내외상관문헌급자료，병진행총결귀납。결과：취을이순수식각취당적방법다양，가응용우제비납미약물재체、제비기인치료적재체、온민성수응효、고분자전약이급조직공정수복재료。결론：취을이순수식적각취당재생물의약영역연구엄범，단상관연구부한우체외，체내연구수진일보계통화심입。
Objective:To provide reference for the intensive study on polyethylene glycol modified chitosan. Methods:The relat-ed literatures at home and abroad were looked up and retrieved from 2004 to 2014, and the related contents were summarized. Results:The methods for the preparation of polyethylene glycol modified chitosan were various. Polyethylene glycol modified chitosan could be used as the carrier for nano-drug and gene therapy, the base of temperature-sensitive hydrogel, polymeric prodrug and the repair mate-rial of tissue engineering. Conclusion:Polyethylene glycol modified chitosan can be wildely used in biomedical field. However, the re-lated research is only in vitro. The in vivo studies should be further systematic and intensive.
