CAJ | 학술논문

目的：探讨抗菌肽与透明质酸复合敷料对二氧化碳点阵激光术后的修复作用。方法：24名受试者的面颊两侧分别接受二氧化碳点阵激光治疗。选择受试者左侧面颊局部外敷抗菌肽与透明质酸复合敷料，每天外用1次，连用5d；另外一侧不作处理。在激光治疗前及治疗后第1、3、7、14d检测面颊两侧经皮水分丢失量、皮肤颜色及皮肤弹性。结果：经过外敷抗菌肽与透明质酸复合敷料一侧面颊的红斑指数、黑素指数和经皮水分丢失量均显著低于对照侧；而皮肤弹性与对照侧差异无统计学意义。结论：二氧化碳点阵激光术后，使用抗菌肽与透明质酸复合敷料可促进皮肤屏障恢复并改善急性炎症反应。
목적：탐토항균태여투명질산복합부료대이양화탄점진격광술후적수복작용。방법：24명수시자적면협량측분별접수이양화탄점진격광치료。선택수시자좌측면협국부외부항균태여투명질산복합부료，매천외용1차，련용5d；령외일측불작처리。재격광치료전급치료후제1、3、7、14d검측면협량측경피수분주실량、피부안색급피부탄성。결과：경과외부항균태여투명질산복합부료일측면협적홍반지수、흑소지수화경피수분주실량균현저저우대조측；이피부탄성여대조측차이무통계학의의。결론：이양화탄점진격광술후，사용항균태여투명질산복합부료가촉진피부병장회복병개선급성염증반응。
Objective To evaluate the benefits of antimicrobial peptides (AMPs) and hyaluronic acid (HA) compound mask on wound healing after fractional carbon dioxide laser resurfacing (FxCR) on human skin. Methods Twenty four subjects were treated with FxCR on the bilateral cheeks. Antimicrobial peptides and hyaluronic acid compound mask was applied on FxCR side of left cheek. The index of erythema,melanin, transepidermal water loss (TEWL),and overall elasticity of FxCR side on both cheeks were measured. Results The index of erythema,melanin,and TEWL of the AMPs and HA compound mask side were significantly lower than those of without mask side. Conclusion Application of AMPs and HA compound mask is an effective method for enhancing wound healing after FxCR,by reducing transient adverse effects such as erythema,hyperpigmentation,and increased TEWL.