CAJ | 학술논문

目的：优选降糖1号中黄芪、地骨皮等水提部分药材的提取工艺条件。方法：建立水提液中黄芪甲苷的RP－HPLC－ELSD含量测定方法。采用正交试验法，以黄芪甲苷得率为指标，考察加水量、提取时间、提取次数对黄芪甲苷得率的影响，优选水提部分药材的提取工艺条件。结果：水提取部分的最优工艺条件为：12倍量水提取3次，每次1 h。结论：优选得到的工艺条件，设计合理，稳定可控，有效成分得率较高。
목적：우선강당1호중황기、지골피등수제부분약재적제취공예조건。방법：건립수제액중황기갑감적RP－HPLC－ELSD함량측정방법。채용정교시험법，이황기갑감득솔위지표，고찰가수량、제취시간、제취차수대황기갑감득솔적영향，우선수제부분약재적제취공예조건。결과：수제취부분적최우공예조건위：12배량수제취3차，매차1 h。결론：우선득도적공예조건，설계합리，은정가공，유효성분득솔교고。
Objective:To optimize extraction process conditions of Astragalus membranaceus, cortex lycii radicis and other water extrac-tion medicinal herbs in hypoglycemic No.1.Methods:To establish a RP-HPLC-ELSD method for determination of astragaloside A in water extraction.The astragaloside A extraction rate was selected as index, using orthogonal test method, the influence of amount of water, extraction time, extraction times on the yield of astragaloside A was investigated, to optimize extraction process conditions of wa-ter extraction medicinal materials.Results:The optimum process conditions of water extraction was as follows:12 times of water and extracting for 3 times, each time is 1 hour.Conclusion: The optimized process conditions is reasonable, stable and controllable, the yield of effective components is high.