中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
16期
100-102
,共3页
脓毒症%肾损伤%炎症因子%血液灌流
膿毒癥%腎損傷%炎癥因子%血液灌流
농독증%신손상%염증인자%혈액관류
Sepsis%Kidney injury%Inflammatory factors%Hemoperfusion
目的：探讨血液灌流对脓毒症急性肾损伤患者炎症因子的疗效，及实施护理措施。方法：选择2013年6月-2014年12月在本院住院治疗的脓毒症并发急性肾损伤患者63例，在患者知情同意后分组，对照组32例，观察组31例，对照组患者给予常规治疗，观察组患者采用血液灌流治疗，比较患者治疗前后hs-CRP、IL-6、IL-10等炎症细胞因子水平的变化、30 d存活率及ICU停留时间。结果：观察组患者和对照组患者治疗后hs-CRP、IL-6、IL-10水平均低于治疗前，观察组患者治疗后低于对照组患者，两组比较差异有统计学意义（P<0.05）。观察组患者30 d存活率高于对照组患者，ICU停留时间少于对照组患者，两组比较差异有统计学意义（P<0.05）。结论：血液灌流能降低脓毒症急性肾损伤患者的炎症因子水平，效果显著，可在临床推广应用。
目的：探討血液灌流對膿毒癥急性腎損傷患者炎癥因子的療效，及實施護理措施。方法：選擇2013年6月-2014年12月在本院住院治療的膿毒癥併髮急性腎損傷患者63例，在患者知情同意後分組，對照組32例，觀察組31例，對照組患者給予常規治療，觀察組患者採用血液灌流治療，比較患者治療前後hs-CRP、IL-6、IL-10等炎癥細胞因子水平的變化、30 d存活率及ICU停留時間。結果：觀察組患者和對照組患者治療後hs-CRP、IL-6、IL-10水平均低于治療前，觀察組患者治療後低于對照組患者，兩組比較差異有統計學意義（P<0.05）。觀察組患者30 d存活率高于對照組患者，ICU停留時間少于對照組患者，兩組比較差異有統計學意義（P<0.05）。結論：血液灌流能降低膿毒癥急性腎損傷患者的炎癥因子水平，效果顯著，可在臨床推廣應用。
목적：탐토혈액관류대농독증급성신손상환자염증인자적료효，급실시호리조시。방법：선택2013년6월-2014년12월재본원주원치료적농독증병발급성신손상환자63례，재환자지정동의후분조，대조조32례，관찰조31례，대조조환자급여상규치료，관찰조환자채용혈액관류치료，비교환자치료전후hs-CRP、IL-6、IL-10등염증세포인자수평적변화、30 d존활솔급ICU정류시간。결과：관찰조환자화대조조환자치료후hs-CRP、IL-6、IL-10수평균저우치료전，관찰조환자치료후저우대조조환자，량조비교차이유통계학의의（P<0.05）。관찰조환자30 d존활솔고우대조조환자，ICU정류시간소우대조조환자，량조비교차이유통계학의의（P<0.05）。결론：혈액관류능강저농독증급성신손상환자적염증인자수평，효과현저，가재림상추엄응용。
Objective:To investigate the efficacy of hemoperfusion in patients with sepsis and acute kidney injury on inflammatory factors,and the implementation of care measures.Method:63 patients with sepsis and acute kidney injury were selected from June 2013 to December 2014 in our hospital,all patients were divided into the control group of 32 cases and the observation group of 31 cases after informed consent of patients.The control group was treated conventional treatment,the observation group was used hemoperfusion treatment.The levels change of inflammatory factors including hs-CRP,IL-6,IL-10,survival rate of 30 d and ICU stay of patients before and after treatment were compared.Result:After treatment,the hs-CRP, IL-6,IL-10 levels in the observation group and the control group were lower than those before treatment,and the observation group were lower than the control group,the differences were statistically significant(P<0.05).The survival rate of 30 d in the observation group was higher than that in the control group,ICU stay was less than that in the control group,the differences were statistically significant (P<0.05).Conclusion:Hemoperfusion can reduce the levels of inflammatory factors in patients with sepsis and acute kidney injury,has significant effect,and can apply in clinical practice.
