CAJ | 학술논문

目的：探讨早期肠内营养支持对重型脑卒中患者免疫功能的影响。方法：选取2011年1月-2014年8月本院收治的110例重型脑卒中患者作为研究对象，采用随机数字表法将所选患者分为研究组和对照组，各55例，研究组给予早期肠内营养支持治疗，对照组给予胃肠外营养支持治疗，疗程为3周，综合比较两组患者治疗前后血红蛋白（Hb）、血清白蛋白（Alb）、甘油三酯（TG）、T淋巴细胞亚群（CD3+、CD4+、CD8+）的变化及并发症发生率。结果：治疗3周后，研究组Hb、Alb、TG均高于对照组，CD3+、CD4+水平高于对照组，CD8+水平显著低于对照组；研究组并发症发生率为10.9%，低于对照组的32.7%，两组比较差异有统计学意义（P<0.05）。结论：早期肠内营养支持治疗应用于重型脑卒中患者效果确切，可有效改善机体营养状况，增强机体免疫力，减少相关并发症，值得临床推广使用。
목적：탐토조기장내영양지지대중형뇌졸중환자면역공능적영향。방법：선취2011년1월-2014년8월본원수치적110례중형뇌졸중환자작위연구대상，채용수궤수자표법장소선환자분위연구조화대조조，각55례，연구조급여조기장내영양지지치료，대조조급여위장외영양지지치료，료정위3주，종합비교량조환자치료전후혈홍단백（Hb）、혈청백단백（Alb）、감유삼지（TG）、T림파세포아군（CD3+、CD4+、CD8+）적변화급병발증발생솔。결과：치료3주후，연구조Hb、Alb、TG균고우대조조，CD3+、CD4+수평고우대조조，CD8+수평현저저우대조조；연구조병발증발생솔위10.9%，저우대조조적32.7%，량조비교차이유통계학의의（P<0.05）。결론：조기장내영양지지치료응용우중형뇌졸중환자효과학절，가유효개선궤체영양상황，증강궤체면역력，감소상관병발증，치득림상추엄사용。
Objective:To investigate the clinical effects of early enteral nutrition support for the immune function of patients with severe stroke.Method:110 patients with severe stroke in our hospital were randomly divided into research group and control group,each contained 55 cases.The research group was treated with early enteral nutrition support therapy.The control group was treated with parenteral nutrition support therapy.The hemoglobin (Hb),serum albumin (Alb),triglyceride (TG),T lymphocyte subsets (CD3+,CD4+,CD8+) before and after treatment and complication rate was compared.Result:After 3 weeks of treatment,the Hb,Alb,TG of the research group was higher than that of the control group,the CD3+,CD4+ was higher than that of the control group,the CD8+ of research group was lower than that of the control group (P<0.05).The complication rate of the research group was 10.9%,which was lower than 32.7% of the control group (P<0.05).Conclusion:Early enteral nutrition support for the immune function of patients with severe stroke has exact effect.It can effectively improve nutritional status, enhance immunity and reduce complications.It’s worthy of clinical widely used.