中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
16期
47-48
,共2页
贝那普利%美托洛尔%老年原发性高血压%心力衰竭
貝那普利%美託洛爾%老年原髮性高血壓%心力衰竭
패나보리%미탁락이%노년원발성고혈압%심력쇠갈
Benazepril%Metoprolol%Elderly essential hypertension%Heart failure
目的：贝那普利联合美托洛尔治疗老年高血压合并心力衰竭患者的临床疗效。方法：随机数字表法将136例老年原发性高血压合并心力衰竭的患者分为两组，每组68例，两组均行基础治疗，对照组采用美托洛尔治疗，观察组采用贝那普利联合美托洛尔治疗。比较两组患者血压、心率及左室舒张末期内经（LVEDD）、左室收缩末期内经（LVESD）、左心室射血分数（LVEF）、6 min步行试验等心功能指标，疗程均为半年。结果：（1）观察组总有效率率为95.59%，对照组为79.41%，观察组总有效率显著高于对照组，比较差异具有统计学意义（P<0.05）。（2）与治疗前比较，两组血压、心率、6 min步行试验、LVEDD、LVESD、LVEF等指标均明显改善，且观察组改善更为明显，比较差异具有统计学意义（P<0.05）。结论：贝那普利联合美托洛尔治疗老年高血压患者降压效果显著，而且还能够改善患者心功能，避免高血压及其心力衰竭并发症的恶化，值得在临床中推广应用。
目的：貝那普利聯閤美託洛爾治療老年高血壓閤併心力衰竭患者的臨床療效。方法：隨機數字錶法將136例老年原髮性高血壓閤併心力衰竭的患者分為兩組，每組68例，兩組均行基礎治療，對照組採用美託洛爾治療，觀察組採用貝那普利聯閤美託洛爾治療。比較兩組患者血壓、心率及左室舒張末期內經（LVEDD）、左室收縮末期內經（LVESD）、左心室射血分數（LVEF）、6 min步行試驗等心功能指標，療程均為半年。結果：（1）觀察組總有效率率為95.59%，對照組為79.41%，觀察組總有效率顯著高于對照組，比較差異具有統計學意義（P<0.05）。（2）與治療前比較，兩組血壓、心率、6 min步行試驗、LVEDD、LVESD、LVEF等指標均明顯改善，且觀察組改善更為明顯，比較差異具有統計學意義（P<0.05）。結論：貝那普利聯閤美託洛爾治療老年高血壓患者降壓效果顯著，而且還能夠改善患者心功能，避免高血壓及其心力衰竭併髮癥的噁化，值得在臨床中推廣應用。
목적：패나보리연합미탁락이치료노년고혈압합병심력쇠갈환자적림상료효。방법：수궤수자표법장136례노년원발성고혈압합병심력쇠갈적환자분위량조，매조68례，량조균행기출치료，대조조채용미탁락이치료，관찰조채용패나보리연합미탁락이치료。비교량조환자혈압、심솔급좌실서장말기내경（LVEDD）、좌실수축말기내경（LVESD）、좌심실사혈분수（LVEF）、6 min보행시험등심공능지표，료정균위반년。결과：（1）관찰조총유효솔솔위95.59%，대조조위79.41%，관찰조총유효솔현저고우대조조，비교차이구유통계학의의（P<0.05）。（2）여치료전비교，량조혈압、심솔、6 min보행시험、LVEDD、LVESD、LVEF등지표균명현개선，차관찰조개선경위명현，비교차이구유통계학의의（P<0.05）。결론：패나보리연합미탁락이치료노년고혈압환자강압효과현저，이차환능구개선환자심공능，피면고혈압급기심력쇠갈병발증적악화，치득재림상중추엄응용。
Objective:To observe benazepril with metoprolol therapy in elderly patients with hypertension combined heart failure clinical curative effect.Method:136 elderly patients with primary hypertension with heart failure were randomly divided into two groups,68 cases in each group,two groups accepted foundation treatment,the control group was treated with metoprolol,the observation group adopted the split with metoprolol therapy.To compare blood pressure,LVEDD,LVESD, LVEF,6 minutes walk test cardiac function indexes of the two groups such as a course of six months.Result:(1) The observation group total effective rate was 95.59%,the control group was 79.41%,the observation group was significantly better than the control group,the difference was statistically significant (P<0.05).(2) Compared before treatment,blood pressure,heart rate,6 min walking test,LVEDD,LVESD,LVEF index of the two groups were significantly improved,with statistically significant difference (P<0.05),the observation group improved more obviously.Conclusion:Benazepril with metoprolol therapy in elderly patients with hypertension antihypertensive effect is remarkable,but also can improve cardiac function in patients with and avoid the deterioration of hypertension and its complications of heart failure,and is worth popularizing in clinical application.
