中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
16期
59-61,62
,共4页
围绝经期综合征%激素替代治疗%倍美力%谷维素
圍絕經期綜閤徵%激素替代治療%倍美力%穀維素
위절경기종합정%격소체대치료%배미력%곡유소
Perimenopausal syndrome%Hormone replacement therapy%Premarin%Oryzanol
目的：研究激素替代疗法治疗围绝经期综合征妇女血E2、FSH水平的影响，探讨其临床适用性。方法：取2013年8月-2014年8月在本院就诊的76例围绝经期综合征患者，随机数字表法分为实验组38例和对照组38例，实验组采用激素替代治疗方法，对照组应用谷维素治疗方法，测定患者治疗前后血E2、FSH水平，比较临床疗效。结果：对照组治疗前后血E2、FSH水平变化不明显，差异无统计学意义（P>0.05）；实验组患者治疗后血E2水平（48.37±17.01）pg/mL比治疗前（28.53±18.55）pg/mL显著升高，治疗后FSH水平（13.01±10.74）IU/L比治疗前（31.02±16.57）显著降低，差异具有统计学意义（P<0.05）。对照组有效率为63.16%，实验组为86.84%，实验组明显高于对照组，差异具有统计学意义（P<0.05）。结论：激素替代治疗方法能使围绝经期综合征妇女血的E2水平显著增加、FSH水平显著降低，提高临床疗效，改善患者生活质量，值得在临床上推广应用。
目的：研究激素替代療法治療圍絕經期綜閤徵婦女血E2、FSH水平的影響，探討其臨床適用性。方法：取2013年8月-2014年8月在本院就診的76例圍絕經期綜閤徵患者，隨機數字錶法分為實驗組38例和對照組38例，實驗組採用激素替代治療方法，對照組應用穀維素治療方法，測定患者治療前後血E2、FSH水平，比較臨床療效。結果：對照組治療前後血E2、FSH水平變化不明顯，差異無統計學意義（P>0.05）；實驗組患者治療後血E2水平（48.37±17.01）pg/mL比治療前（28.53±18.55）pg/mL顯著升高，治療後FSH水平（13.01±10.74）IU/L比治療前（31.02±16.57）顯著降低，差異具有統計學意義（P<0.05）。對照組有效率為63.16%，實驗組為86.84%，實驗組明顯高于對照組，差異具有統計學意義（P<0.05）。結論：激素替代治療方法能使圍絕經期綜閤徵婦女血的E2水平顯著增加、FSH水平顯著降低，提高臨床療效，改善患者生活質量，值得在臨床上推廣應用。
목적：연구격소체대요법치료위절경기종합정부녀혈E2、FSH수평적영향，탐토기림상괄용성。방법：취2013년8월-2014년8월재본원취진적76례위절경기종합정환자，수궤수자표법분위실험조38례화대조조38례，실험조채용격소체대치료방법，대조조응용곡유소치료방법，측정환자치료전후혈E2、FSH수평，비교림상료효。결과：대조조치료전후혈E2、FSH수평변화불명현，차이무통계학의의（P>0.05）；실험조환자치료후혈E2수평（48.37±17.01）pg/mL비치료전（28.53±18.55）pg/mL현저승고，치료후FSH수평（13.01±10.74）IU/L비치료전（31.02±16.57）현저강저，차이구유통계학의의（P<0.05）。대조조유효솔위63.16%，실험조위86.84%，실험조명현고우대조조，차이구유통계학의의（P<0.05）。결론：격소체대치료방법능사위절경기종합정부녀혈적E2수평현저증가、FSH수평현저강저，제고림상료효，개선환자생활질량，치득재림상상추엄응용。
Objective:To study the effect of hormone replacement therapy on blood FSH and E2 levels of perimenopausal syndrome women and explore the clinical applicability.Method:76 perimenopausal syndrome cases were selected and divided into two groups,38 cases in each group.The observation group was treated with hormone replacement therapy,the control group was treated with oryzanol tablets,the blood FSH and E2 levels and the clinical effect were compared.Result:The changes of blood FSH and E2 levels of the control group were not obvious,the difference was not statistically significant(P>0.05).The blood E2 level after therapy(48.37±17.01)pg/mL was higher than before(28.53±18.55)pg/mL,the blood FSH level after therapy (13.01±10.74)IU/L was lower than before(31.02±16.57)IU/L in the observation group,the difference was statistically significant(P<0.05).Clinical effective rate was 86.84% in the observation group and 63.16% in the control group,the difference was statistically significant(P<0.05).Conclusion:Hormone replacement therapy used in perimenopausal syndrome women can decrease FSH level,increase E2 level and improve the clinical effect,it is suitable for clinical application.
