中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
16期
19-21
,共3页
白云洋%张婷婷%边渼慧%戴子琪%韩丽彤%韩静艳%徐晶
白雲洋%張婷婷%邊渼慧%戴子琪%韓麗彤%韓靜豔%徐晶
백운양%장정정%변미혜%대자기%한려동%한정염%서정
帕罗西汀%强迫性障碍%认知行为治疗
帕囉西汀%彊迫性障礙%認知行為治療
파라서정%강박성장애%인지행위치료
Paroxetine%Obsessive-compulsive disorder%Cognitive behavior therapy
目的：评价帕罗西汀单药治疗及联合认知行为治疗强迫性障碍的疗效和安全性。方法：将60例强迫性障碍患者且Yale-Brown强迫量表（Y-Bocs）评分≥16分随机数字表法分为研究组（帕罗西汀联合认知行为治疗）和对照组（单用帕罗西汀治疗），每组各30例，治疗疗程为5个月。治疗前及治疗1、2、3、4、5个月时采用Y-Bocs评定疗效。结果：两组治疗后Y-Bocs评分较治疗前均显著降低，且研究组较对照组更为显著。两组不良反应少而轻微。结论：帕罗西汀联合认知行为治疗强迫性障碍较单用帕罗西汀疗效更好。
目的：評價帕囉西汀單藥治療及聯閤認知行為治療彊迫性障礙的療效和安全性。方法：將60例彊迫性障礙患者且Yale-Brown彊迫量錶（Y-Bocs）評分≥16分隨機數字錶法分為研究組（帕囉西汀聯閤認知行為治療）和對照組（單用帕囉西汀治療），每組各30例，治療療程為5箇月。治療前及治療1、2、3、4、5箇月時採用Y-Bocs評定療效。結果：兩組治療後Y-Bocs評分較治療前均顯著降低，且研究組較對照組更為顯著。兩組不良反應少而輕微。結論：帕囉西汀聯閤認知行為治療彊迫性障礙較單用帕囉西汀療效更好。
목적：평개파라서정단약치료급연합인지행위치료강박성장애적료효화안전성。방법：장60례강박성장애환자차Yale-Brown강박량표（Y-Bocs）평분≥16분수궤수자표법분위연구조（파라서정연합인지행위치료）화대조조（단용파라서정치료），매조각30례，치료료정위5개월。치료전급치료1、2、3、4、5개월시채용Y-Bocs평정료효。결과：량조치료후Y-Bocs평분교치료전균현저강저，차연구조교대조조경위현저。량조불량반응소이경미。결론：파라서정연합인지행위치료강박성장애교단용파라서정료효경호。
Objective:To evaluate the curative effect and safety of paroxetine with cognitive behavior therapy. Method:60 obsessive-compulsive disorder patients with Yale-Brown obsessive-compulisive scale (Y-Bocs) score ≥16 were randomly divided into study group (treated with paroxetine and cognitive behavior therapy for 5 months) and control group (treated with paroxetine for 5 months),clinical effect was assessed with Yale-Brown obsessive-compulisive scale (Y-Bocs)and treatment emergent symptom scale (TESS),month 1,2,3,4 and 5.Result:Compared with the control group,the study group showed more Y-Bocs score decrease,although both groups Y-Bocs score decreased after treatment.The side effects of the two groups were fewer and lighter.Conclusion:Paroxetine with cognitive behavior therapy demonstrates more treatment effects than paroxetine only for patients with obsessive-compulsive disorder (OCD).
