临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2015年
16期
32-33
,共2页
胃溃疡%奥美拉唑%雷贝拉唑%西咪替丁
胃潰瘍%奧美拉唑%雷貝拉唑%西咪替丁
위궤양%오미랍서%뢰패랍서%서미체정
Gastric ulcer%Omeprazole%Rabeprazole%Cimetidine
目的：观察不同给药方法治疗胃溃疡的临床疗效。方法将116例胃溃疡患者随机分为A、B、C组， A组39例患者采用的雷贝拉唑溶于葡萄糖溶液治疗法，B组39例采用的奥美拉唑溶于葡萄糖溶液治疗法，C组38例采用西咪替丁治疗法，治疗3周后观察临床疗效、并发症发生率及患者满意度。结果 A组、B组、C组患者病情都得到一定程度的改善，其中，A组治疗总有效率为94．87％明显高于B组的89．74％和C组的89．47％，并发症发生率低于B组、C组，满意度明显优于B组、C组，差异有统计学意义（P＜0．05）；B组与C组治疗总有效率并发症发生率及患者满意度差异无统计学意义（ P＞0．05）。结论雷贝拉唑治疗胃溃疡可收到良好的疗效，值得临床推广应用。
目的：觀察不同給藥方法治療胃潰瘍的臨床療效。方法將116例胃潰瘍患者隨機分為A、B、C組， A組39例患者採用的雷貝拉唑溶于葡萄糖溶液治療法，B組39例採用的奧美拉唑溶于葡萄糖溶液治療法，C組38例採用西咪替丁治療法，治療3週後觀察臨床療效、併髮癥髮生率及患者滿意度。結果 A組、B組、C組患者病情都得到一定程度的改善，其中，A組治療總有效率為94．87％明顯高于B組的89．74％和C組的89．47％，併髮癥髮生率低于B組、C組，滿意度明顯優于B組、C組，差異有統計學意義（P＜0．05）；B組與C組治療總有效率併髮癥髮生率及患者滿意度差異無統計學意義（ P＞0．05）。結論雷貝拉唑治療胃潰瘍可收到良好的療效，值得臨床推廣應用。
목적：관찰불동급약방법치료위궤양적림상료효。방법장116례위궤양환자수궤분위A、B、C조， A조39례환자채용적뢰패랍서용우포도당용액치요법，B조39례채용적오미랍서용우포도당용액치요법，C조38례채용서미체정치요법，치료3주후관찰림상료효、병발증발생솔급환자만의도。결과 A조、B조、C조환자병정도득도일정정도적개선，기중，A조치료총유효솔위94．87％명현고우B조적89．74％화C조적89．47％，병발증발생솔저우B조、C조，만의도명현우우B조、C조，차이유통계학의의（P＜0．05）；B조여C조치료총유효솔병발증발생솔급환자만의도차이무통계학의의（ P＞0．05）。결론뢰패랍서치료위궤양가수도량호적료효，치득림상추엄응용。
Objective To observe the clinical effect of different administration methods in clinic for the treatment of gastric ulcer,improve the cure rate of gastric ulcer .Methods 116 patients with gastric ulcer were randomly divided into three groups.Group A of 39 patients with rabeprazole was dissolved in glucose solution treatment .Group B of 39 patients with ome-prazole soluble in glucose solution treatment .Group C of 38 cases use of cimetidine therapy ,After 3 weeks treatment ,observed the clinical efficacy,the rate of complications and patient satisfaction of the three group .Results Group A,group B,group C patients were improved to a certain extent ,among them,the total effective rate of group A was (94.87%) obviously higher than that of group B(89.74%) and group C(89.47%),the difference was statistically significant (P<0.05).The difference of to-tal effective rate between group B and group C was not statistically significant ( P>0.05).Patients complication rate of the group A was lower than that of group B and group C ,the degree of satisfaction of patients was better than that of group B and group C,the difference were statistically significant (P<0.05).Differences in the rate of complication and patient satisfaction between group B and group C were not statistically significant (P>0.05).Conclusion The rabeprazole has a good curative effect on gastric ulcer , which is better than that of omeprazole and cimetidine .It is worthy of clinical application .
