CAJ | 학술논문

目的：探讨超高速剪切波弹性成像在宫颈癌前病变及宫颈浸润癌诊断中的价值。方法利用超高速弹性剪切波对经过筛选的78例已婚成年女性进行诊断，选择其中TCT提示无上皮内瘤样病变者30例，设为A组(正常组)；TCT提示鳞状细胞异常且经病理确诊为癌前病变者(即CINⅠ、Ⅱ、Ⅲ)30例，设为B组；TCT及病理均提示鳞状细胞癌且临床分期为Ⅰb期者18例，设为C组。所有受试者均进行常规二维彩色多普勒及经阴道超高速剪切波弹性成像检查，以便获得杨氏模量平均值。结果 A组的超高速剪切波弹性成像杨氏模量平均值为(21.81±3.87) kPa，B组为(21.27±3.21) kPa，两组比较差异无统计学意义(P>0.05)；C组病灶的杨氏模量平均值为(97.55±87.17) kPa，C组病灶周围正常组织的杨氏模量平均值为(24.47±9.66) kPa，两组比较差异具有统计学意义(P<0.05)。结论超高速剪切波弹性成像技术在宫颈癌前病变诊断上没有明显帮助，但能给宫颈浸润癌的诊断提供有价值的信息。
목적：탐토초고속전절파탄성성상재궁경암전병변급궁경침윤암진단중적개치。방법이용초고속탄성전절파대경과사선적78례이혼성년녀성진행진단，선택기중TCT제시무상피내류양병변자30례，설위A조(정상조)；TCT제시린상세포이상차경병리학진위암전병변자(즉CINⅠ、Ⅱ、Ⅲ)30례，설위B조；TCT급병리균제시린상세포암차림상분기위Ⅰb기자18례，설위C조。소유수시자균진행상규이유채색다보륵급경음도초고속전절파탄성성상검사，이편획득양씨모량평균치。결과 A조적초고속전절파탄성성상양씨모량평균치위(21.81±3.87) kPa，B조위(21.27±3.21) kPa，량조비교차이무통계학의의(P>0.05)；C조병조적양씨모량평균치위(97.55±87.17) kPa，C조병조주위정상조직적양씨모량평균치위(24.47±9.66) kPa，량조비교차이구유통계학의의(P<0.05)。결론초고속전절파탄성성상기술재궁경암전병변진단상몰유명현방조，단능급궁경침윤암적진단제공유개치적신식。
Objective To discuss the value of shear wave elastography (SWE) in the diagnosis of cervical precancerous lesions and invasive cervical carcinoma. Methods Seventy-eight adult women received conventional two-dimensional color Doppler and transvaginal SWE to acquire the average value of Young's modulus value. The pa-tients were divided into three groups: group A (30 patients, no intraepithelial neoplasia disorders by CTC), group B [(30 patients, with abnormal squamous cell by TCT and were confirmed by pathology as cervical intraepithelial neo-plasia (CINⅠ,Ⅱ,Ⅲ)], group C (18 patients, squamous-cell carcinoma by both TCT and pathology, with the clinical stages ofⅠb). Results The average maximum value of Young's modulus value of SWE was (21.81 ± 3.87) kPa in group A, (21.27±3.21) kPa in group B, with no statistically significant difference between the two groups (P>0.05). In Group C, the Young's modulus value of lesion was (97.55±87.17) kPa, and that of normal tissue around the lesion was (24.47±9.66) kPa, with statistically significant difference (P<0.05). Conclusion Shear wave elastography brings no significant benefits in the diagnosis of cervical precancerous lesions, but it can provide valuable information for the di-agnosis of invasive cervical carcinoma.