安徽医药
安徽醫藥
안휘의약
ANHUI MEDICAL AND PHARMACEUTICAL JOURNAL
2015年
6期
1111-1114
,共4页
乏血供%肝肿瘤%化学栓塞%射频消融
乏血供%肝腫瘤%化學栓塞%射頻消融
핍혈공%간종류%화학전새%사빈소융
blood supply%liver neoplasms%chemoembolization%radiofrequency ablation
目的：探讨经导管动脉化学栓塞（transcatheter arterial chemoembolization，TACE）联合射频消融（radiofrequency ablation， RFA）治疗晚期乏血供大肝癌的疗效。方法回顾性分析该院2008年10月—2014年7月收治的40例晚期乏血供大肝癌患者的临床资料，随机分为两组：联合组（TACE联合RFA治疗，21例）、对照组（单纯TACE治疗，19例）。比较两组术后血清甲胎蛋白（AFP）、肿瘤完全坏死率、肿瘤缩小率、肿瘤进展率、术后肝功能变化等指标。结果术后6个月联合治疗组肿瘤缩小率、完全坏死率和肿瘤进展率分别为90．47％、71．43％和14．29％，对照组的分别为63．19％、36．84％和47．37％。两组差异具有统计学意义（P均＜0．05）。结论 TACE联合RFA治疗乏血供肝癌较仅行TACE治疗能提供更好的疗效。
目的：探討經導管動脈化學栓塞（transcatheter arterial chemoembolization，TACE）聯閤射頻消融（radiofrequency ablation， RFA）治療晚期乏血供大肝癌的療效。方法迴顧性分析該院2008年10月—2014年7月收治的40例晚期乏血供大肝癌患者的臨床資料，隨機分為兩組：聯閤組（TACE聯閤RFA治療，21例）、對照組（單純TACE治療，19例）。比較兩組術後血清甲胎蛋白（AFP）、腫瘤完全壞死率、腫瘤縮小率、腫瘤進展率、術後肝功能變化等指標。結果術後6箇月聯閤治療組腫瘤縮小率、完全壞死率和腫瘤進展率分彆為90．47％、71．43％和14．29％，對照組的分彆為63．19％、36．84％和47．37％。兩組差異具有統計學意義（P均＜0．05）。結論 TACE聯閤RFA治療乏血供肝癌較僅行TACE治療能提供更好的療效。
목적：탐토경도관동맥화학전새（transcatheter arterial chemoembolization，TACE）연합사빈소융（radiofrequency ablation， RFA）치료만기핍혈공대간암적료효。방법회고성분석해원2008년10월—2014년7월수치적40례만기핍혈공대간암환자적림상자료，수궤분위량조：연합조（TACE연합RFA치료，21례）、대조조（단순TACE치료，19례）。비교량조술후혈청갑태단백（AFP）、종류완전배사솔、종류축소솔、종류진전솔、술후간공능변화등지표。결과술후6개월연합치료조종류축소솔、완전배사솔화종류진전솔분별위90．47％、71．43％화14．29％，대조조적분별위63．19％、36．84％화47．37％。량조차이구유통계학의의（P균＜0．05）。결론 TACE연합RFA치료핍혈공간암교부행TACE치료능제공경호적료효。
Objective To investigate the value of the combined treatment of transcatheter arterial chemoemhnbolization (TACE)and radiofrequency ablation (RFA)for poor blood supply hepatocarcinoma.Methods 40 cases of poor blood supply large hepatocarcinoma (from October 2008 to July 2014 )patients was divided into two groups:Combination therapy group (treated by TACE in combination with RFA,n=21)and Control group (treated by TACE alone,n=19).postoperative AFP,complete tumor necrosis rate,tumor shrink rate,tumor progression rate and postoperative liver function were detected in the two groups.Results Complete tumor necrosis rate,tumor shrink rate,tumor progression rate rates in 6 months after Interventional surgery of combination therapy group were 90.47%,71.4 % and 14.29%,respectively.While in the control group,complete tumor necrosis rate,tumor shrink rate,tumor pro-gression rate rates were 63.19%,36.84% and 47.37%.There were significant difference of these data between combination therapy group and control group (P<0.05).Conclusion Combination therapy of multipolar RFA and TACE maybe more efficiently to treat poor blood supply hepatocarcinoma than use TACE alone.
