CAJ | 학술논문

目的：对比分析奥美拉唑和西咪替丁治疗应激性胃溃疡的临床效果。方法：选取2011年9月—2014年8月在消化内科治疗的110例应激性胃溃疡患者，将其随机分为对照组和研究组，各55例，所有患者均进行常规的基础治疗，对照组采用西咪替丁治疗，研究组采用奥美拉唑治疗，比较两组患者的临床治疗效果。结果：研究组患者的止血时间短于对照组，差异有统计学意义（ P＜0.05）；总有效率研究组94.5％，对照组80.0％，研究组明显高于对照组（ P＜0.05）；研究组患者治疗后的胃液pH高于对照组，血清促胃液素低于对照组，差异有统计学意义（ P＜0.05）。结论：应用奥美拉唑优于西咪替丁治疗应激性溃疡，临床效果较好。
목적：대비분석오미랍서화서미체정치료응격성위궤양적림상효과。방법：선취2011년9월—2014년8월재소화내과치료적110례응격성위궤양환자，장기수궤분위대조조화연구조，각55례，소유환자균진행상규적기출치료，대조조채용서미체정치료，연구조채용오미랍서치료，비교량조환자적림상치료효과。결과：연구조환자적지혈시간단우대조조，차이유통계학의의（ P＜0.05）；총유효솔연구조94.5％，대조조80.0％，연구조명현고우대조조（ P＜0.05）；연구조환자치료후적위액pH고우대조조，혈청촉위액소저우대조조，차이유통계학의의（ P＜0.05）。결론：응용오미랍서우우서미체정치료응격성궤양，림상효과교호。
Objective:To compare and analyze the effect of omeprazole and cimetidine for stress gastric ulcer.Methods:From September 2011 to August 2011,110 cases with stress gastric ulcer were treated in digestion medicine,they were random-ly divided into control group and study group,55 cases in each group,all patients accepted conventional treatment,the control group were treated by cimetidine,the study group were treated by omeprazole,the clinical effect was compared. Results:The bleeding time of study group was shorter than the control group,the difference was statistically significant(P<0. 05). The total effective rate of study group was 94. 5%,the total effective rate of control group was 80. 0%,study group was significantly higher than control group(P<0. 05). The gastric juice in study group was higher than control group,the serum gastrin in study group lower than the control group(P<0. 05). Conclusion:The clinical effect of was omeprazole and cimetidine for stress gas-tric ulcer is better,can provide guidance for clinical research.