CAJ | 학술논문

目的：探讨血清前列腺特异性抗原（ PSA）联合酸性磷酸酶（ PAP）检测对前列腺癌患者的诊断价值。方法：采用化学发光分析法对96例诊断为前列腺癌的患者、48例前列腺增生患者以及48例正常男性的血清PSA，PAP进行测定。结果：PSA检出前列腺癌的灵敏性为93.75％，特异性为72.38％；PAP对前列腺癌的灵敏性为70.83％，特异性为89.11％。结论：PSA对前列腺癌的疗效监测和筛选诊断有较大的价值，而PAP不适合用于前列腺癌的筛检，PSA可以完全替代PAP对前列腺癌的疗效和预后的监视作用；但PSA联合PAP检测能够有效提高前列腺癌的诊断率以及鉴别前列腺癌与前列腺增生的准确性，具有较大的临床应用价值。
목적：탐토혈청전렬선특이성항원（ PSA）연합산성린산매（ PAP）검측대전렬선암환자적진단개치。방법：채용화학발광분석법대96례진단위전렬선암적환자、48례전렬선증생환자이급48례정상남성적혈청PSA，PAP진행측정。결과：PSA검출전렬선암적령민성위93.75％，특이성위72.38％；PAP대전렬선암적령민성위70.83％，특이성위89.11％。결론：PSA대전렬선암적료효감측화사선진단유교대적개치，이PAP불괄합용우전렬선암적사검，PSA가이완전체대PAP대전렬선암적료효화예후적감시작용；단PSA연합PAP검측능구유효제고전렬선암적진단솔이급감별전렬선암여전렬선증생적준학성，구유교대적림상응용개치。
Objective:To investigate the serum prostate specific antigen(PSA)and acid phosphatase(PAP)in diagnosis of prostate cancer. Methods:To mensurate serum PSA,PAP of 96 cases diagnosed with prostate cancer,48 patients with benign prostatic hyperplasia and 48 cases of normalmale. Results:The sensitivity of PSA detection of prostate cancer was 93. 75%,the specificity was 72. 38%. The sensitivity of PAP in prostate cancer was 70. 83%,the specificity was 89. 11%. Conclusion:PSA has great value for prostate cancer screening and monitoring and diagnosis,PAP is not suitable for screening for prostate canc-er,monitoring PSA can completely replace the curative effect and prognosis of PAP on prostate cancer. But the detection of PSA combined with PAP can improve the diagnosis rate of prostate cancer and diagnosis of prostate cancer and benign prostatic hy-perplasia,is of great clinical value.