临床医药实践
臨床醫藥實踐
림상의약실천
PROCEEDING OF CLINICAL MEDICINE
2015年
6期
408-410,411
,共4页
动脉介入栓塞%射频消融%小肝癌
動脈介入栓塞%射頻消融%小肝癌
동맥개입전새%사빈소융%소간암
hepatic artery interventional embolization%radiofrequency ablation%small liver cancer
目的:评价动脉介入栓塞联合射频消融术在小肝癌术后复发中的应用价值。方法:将68例小肝癌术后复发患者随机分为观察组和对照组,分别采用动脉介入栓塞联合射频消融治疗和单纯动脉介入栓塞治疗,观察甲胎蛋白( AFP)变化,监测肿瘤大小,复查随访并统计生存率及总有效率。结果:治疗1周后,两组AFP值均较治疗前显著下降(P<0.05),但观察组下降程度大于对照组(P<0.05)。治疗1个月后,观察组总有效率(89.5%)优于对照组(66.7%),差异有统计学意义( P<0.05)。随访3年,观察组1年、2年、3年生存率分别为94.7%,86.8%和78.9%;对照组1年、2年、3年生存率分别为93.3%,80.0%和66.7%,两组患者1年生存率差异无统计学意义( P>0.05);观察组2年、3年生存率较对照组高( P<0.05)。结论:两种方法联合治疗较单一动脉介入栓塞治疗效果好,且提高了生存率。
目的:評價動脈介入栓塞聯閤射頻消融術在小肝癌術後複髮中的應用價值。方法:將68例小肝癌術後複髮患者隨機分為觀察組和對照組,分彆採用動脈介入栓塞聯閤射頻消融治療和單純動脈介入栓塞治療,觀察甲胎蛋白( AFP)變化,鑑測腫瘤大小,複查隨訪併統計生存率及總有效率。結果:治療1週後,兩組AFP值均較治療前顯著下降(P<0.05),但觀察組下降程度大于對照組(P<0.05)。治療1箇月後,觀察組總有效率(89.5%)優于對照組(66.7%),差異有統計學意義( P<0.05)。隨訪3年,觀察組1年、2年、3年生存率分彆為94.7%,86.8%和78.9%;對照組1年、2年、3年生存率分彆為93.3%,80.0%和66.7%,兩組患者1年生存率差異無統計學意義( P>0.05);觀察組2年、3年生存率較對照組高( P<0.05)。結論:兩種方法聯閤治療較單一動脈介入栓塞治療效果好,且提高瞭生存率。
목적:평개동맥개입전새연합사빈소융술재소간암술후복발중적응용개치。방법:장68례소간암술후복발환자수궤분위관찰조화대조조,분별채용동맥개입전새연합사빈소융치료화단순동맥개입전새치료,관찰갑태단백( AFP)변화,감측종류대소,복사수방병통계생존솔급총유효솔。결과:치료1주후,량조AFP치균교치료전현저하강(P<0.05),단관찰조하강정도대우대조조(P<0.05)。치료1개월후,관찰조총유효솔(89.5%)우우대조조(66.7%),차이유통계학의의( P<0.05)。수방3년,관찰조1년、2년、3년생존솔분별위94.7%,86.8%화78.9%;대조조1년、2년、3년생존솔분별위93.3%,80.0%화66.7%,량조환자1년생존솔차이무통계학의의( P>0.05);관찰조2년、3년생존솔교대조조고( P<0.05)。결론:량충방법연합치료교단일동맥개입전새치료효과호,차제고료생존솔。
Objective:To evaluate the value of treatmen of tartery interventional embolization and radofrequency ablation for the recurrence of small liver cancer. Methods:Sixty-eight patients of the recurrence of small liver cancer were randomly di-vided into observation group and control group,the hepatic artery interventional embolization with radiofrequency ablation thera-py and simple hepatic artery interventional embolization,observing alpha-fetoprotein( AFP),monitoring of tumor size,review and follow-up survival rate and total effective rate of statistics. Results:After one week of treatment,two groups was significant reduction in the AFP value ( P < 0 . 0 5 ),but the observation group decreased greater more than cntrol group ( P < 0 . 0 5 ). After one month of treatment ,the total effective rate of observation group( 8 9 . 5 % )is better than that of control group (66. 7%),the difference was statistically significant(P<0. 05). After three years follow-up,the survival rate of observation group when it was one,two,three years was respectively 94. 7%,86. 8%and 78. 9%;In the control group,one,two,three years survival rate are respectively 93. 3%,80. 0%and66. 7%. The survival rate was no statistically significant difference one year (P>0. 05);The survival rate in observation group was higher than control group in two,three years(P<0. 05). Conclusion:The effect is more good of two methods of combination therapy than single interventional embolization treatment,and improve the survival rate.