医学临床研究
醫學臨床研究
의학림상연구
JOURNAL OF CLINICAL RESEARCH
2015年
5期
937-938,941
,共3页
排卵诱导%胚胎移植%妊娠率%受精 ,体外%卵泡刺激素
排卵誘導%胚胎移植%妊娠率%受精 ,體外%卵泡刺激素
배란유도%배태이식%임신솔%수정 ,체외%란포자격소
Ovulation Induction%Embryo T ransfer%Pregnancy Rate%Fertilization in Vitro%Fol-licle Stimulating Hormone
【目的】探讨在体外受精‐胚胎移植（IVF‐ET ）治疗中采用超常方案降调节后分别使用尿源性卵泡刺激素（u‐FSH）和基因重组FSH（r‐FSH）联合尿促性腺激素（HMG）促排后的临床结局。【方法】回顾性分析2013年1～12本院生殖中心559例接受IVF或卵胞浆单精子注射（ICSI）助孕治疗的临床结局。【结果】两组患者促性腺激素（gonadotropin ，Gn）天数、Gn使用剂量，获卵数、受精率、卵裂率、妊娠率、可利用胚胎数、种植率、流产率、异位妊娠率、卵巢过度刺激综合征（OHSS）发生率均无显著差异（ P ＞0．05）。【结论】IVF‐ET中超长方案降调节后u‐FSH联合HMG和r‐FSH联合 HMG促排卵的效果相当。
【目的】探討在體外受精‐胚胎移植（IVF‐ET ）治療中採用超常方案降調節後分彆使用尿源性卵泡刺激素（u‐FSH）和基因重組FSH（r‐FSH）聯閤尿促性腺激素（HMG）促排後的臨床結跼。【方法】迴顧性分析2013年1～12本院生殖中心559例接受IVF或卵胞漿單精子註射（ICSI）助孕治療的臨床結跼。【結果】兩組患者促性腺激素（gonadotropin ，Gn）天數、Gn使用劑量，穫卵數、受精率、卵裂率、妊娠率、可利用胚胎數、種植率、流產率、異位妊娠率、卵巢過度刺激綜閤徵（OHSS）髮生率均無顯著差異（ P ＞0．05）。【結論】IVF‐ET中超長方案降調節後u‐FSH聯閤HMG和r‐FSH聯閤 HMG促排卵的效果相噹。
【목적】탐토재체외수정‐배태이식（IVF‐ET ）치료중채용초상방안강조절후분별사용뇨원성란포자격소（u‐FSH）화기인중조FSH（r‐FSH）연합뇨촉성선격소（HMG）촉배후적림상결국。【방법】회고성분석2013년1～12본원생식중심559례접수IVF혹란포장단정자주사（ICSI）조잉치료적림상결국。【결과】량조환자촉성선격소（gonadotropin ，Gn）천수、Gn사용제량，획란수、수정솔、란렬솔、임신솔、가이용배태수、충식솔、유산솔、이위임신솔、란소과도자격종합정（OHSS）발생솔균무현저차이（ P ＞0．05）。【결론】IVF‐ET중초장방안강조절후u‐FSH연합HMG화r‐FSH연합 HMG촉배란적효과상당。
[Objective] To compare the clinical efficacy of in vitro fertilization‐embryo transfer (IVF‐ET ) versus two different kinds of follicle‐stimulating hormone (FSH) stimulation protocols for controlled hyper‐stimulation after super‐long down‐regulation .[Methods]A total of 559 IVF/intracytoplasmic sperm injection (ICSI)‐ET cycles in in‐fertile patients at our reproductive center from January to November 2013 were analyzed retrospectively .According to the ovarian stimulation protocolr‐FSH+75IUHMG ,they were divided into two groups of gonal‐F ( n =294) and urofollitropin group ( n=265) .The clinical outcomes were compared between two groups .[Results]The total dos‐age of gonadotropin ,duration of gonadotropin stimulation ,estradiol level on HCG day ,number of retrieved oocytes , fertilization rate ,number of tranferable embryos ,clinical pregnancy rate ,implantation rate ,abortion rate ,rate of ec‐topic pregnancy and incidence of ovarian hyperstimulation syndrome were not significantly different between two groups ( P>0 .05) .[Conclusion]A combination of u‐FSH or r‐FSH and HMG have the same effectiveness in ovari‐an stimulation during IVF‐ET cycles after super‐long down‐regulation .
