CAJ | 학술논문

目的探讨患者健康问卷抑郁量表(patient health questionnaire-9,PHQ-9)在综合医院心身疾病门诊对抑郁筛查的可行性并分析抑郁发生的相关因素.方法 258例患者自行完成PHQ-9及世界卫生组织生活质量测定量表简表(the world health questionnaire quality of life brief questionnaire,WHOQOL-BREF)的评估并接受汉密尔顿抑郁量表(Hamilton depression rating sca-le,HAMD-17)评定.抽取其中97例患者进行美国精神障碍诊断与统计手册DSM-Ⅳ轴Ⅰ障碍临床定式检查(structured clinical interview for DSM-Ⅳaxis Ⅰ disorders,SCID),进行PHQ-9的效度研究.按PHQ-9是否≥5分分为有抑郁症状群组和无抑郁症状群组,分析抑郁发生的相关因素.结果 ①PHQ-9的特异度为67％,灵敏度为98％,Kappa值为0.664.PHQ-9总分与HAMD总分显著相关,相关系数为0.75 (P＜0.01).②单因素分析发现年龄、家庭人均月收入、对自己当前的健康状况满意程度、生存质量满意程度与抑郁的发生有关.多因素Logistic回归分析显示:年龄、健康状况、生活质量是影响抑郁发生的主要因素.结论 PHQ-9可作为抑郁症状的筛查工具以提高抑郁识别率.年龄、健康状况、生存质量是影响抑郁发生的主要因素.
목적 탐토환자건강문권억욱량표(patient health questionnaire-9,PHQ-9)재종합의원심신질병문진대억욱사사적가행성병분석억욱발생적상관인소.방법 258례환자자행완성PHQ-9급세계위생조직생활질량측정량표간표(the world health questionnaire quality of life brief questionnaire,WHOQOL-BREF)적평고병접수한밀이돈억욱량표(Hamilton depression rating sca-le,HAMD-17)평정.추취기중97례환자진행미국정신장애진단여통계수책DSM-Ⅳ축Ⅰ장애림상정식검사(structured clinical interview for DSM-Ⅳaxis Ⅰ disorders,SCID),진행PHQ-9적효도연구.안PHQ-9시부≥5분분위유억욱증상군조화무억욱증상군조,분석억욱발생적상관인소.결과 ①PHQ-9적특이도위67％,령민도위98％,Kappa치위0.664.PHQ-9총분여HAMD총분현저상관,상관계수위0.75 (P＜0.01).②단인소분석발현년령、가정인균월수입、대자기당전적건강상황만의정도、생존질량만의정도여억욱적발생유관.다인소Logistic회귀분석현시:년령、건강상황、생활질량시영향억욱발생적주요인소.결론 PHQ-9가작위억욱증상적사사공구이제고억욱식별솔.년령、건강상황、생존질량시영향억욱발생적주요인소.
Objective To explore the feasibility of patient health questionnaire-9 (PHQ-9) in a general hospital outpatients and analyze the risk factors of depressive syndromes.Methods Two hundred fifty-eight outpatients filled out PHQ-9 and the World Health Questionnaire Quality of Life Brief Questionnaire(WHOQOL-BREF) by themselves.Then they were evaluated by professionals with Hamilton Depression Rating Scale (HAMD-17).Ninety-seven of them were further interviewed with the Structured Clinical Interview for DSM-Ⅳ Disorders(SCID) for the diagnosis of major depression which in order to analyze the validity of the PHQ-9.All patients were divided into the depressive group and non-depressive group according the score of PHQ-9,and then analyzed the risk factors of depression.Results ①The sensitivity of PHQ-9 was 98％,the specificity was 67％ and Kappa was 0.664.The total score of PHQ-9 was high correlated with the total score of HAMD,the coefficient was 0.75(P＜0.01).②The Univariate analysis showed that the depressive symptom was associated with age,monthly income,health status,the quality of life.Logistic regression analysis showed that age,health status,the quality of life were the main factors of depression.Conclusion PHQ-9 may svere as a screening tool to increase the recognition of depression and age,health status,the quality of life were the main factors of depression.