CAJ | 학술논문

目的：探讨牙周源性牙周牙髓联合病变患牙微生物感染的菌种及影响因素。方法选择2012年1月至2013年12月来武汉市汉口医院就诊的牙周源性牙周牙髓联合病变患者和正常正畸拔除者各32例（32颗）为研究对象，采集样本的牙周袋、根管标本，检测标本中微生物的感染情况及其牙周源性牙周牙髓联合病变发病的影响因素。结果32例牙周源性牙周牙髓联合病变样本中微生物感染的检出率为46．9％，以奈瑟菌属、棒状杆菌属、放线菌属、弯曲菌属、梭杆菌属以及嗜血杆菌属为主。32例正常对照样本中微生物感染的检出率为18．8％，主要为奈瑟菌属、放线菌属和弯曲菌属。奈瑟菌属、棒状杆菌属、放线菌属、梭杆菌属和嗜血杆菌属感染为牙周源性牙周牙髓联合病变发生的主要影响因素。结论微生物感染的种类与牙周源性牙周牙髓联合病变的发生密切相关，临床应采取不同的治疗方案以提高联合病变的治愈率、降低患者失牙率。
목적：탐토아주원성아주아수연합병변환아미생물감염적균충급영향인소。방법선택2012년1월지2013년12월래무한시한구의원취진적아주원성아주아수연합병변환자화정상정기발제자각32례（32과）위연구대상，채집양본적아주대、근관표본，검측표본중미생물적감염정황급기아주원성아주아수연합병변발병적영향인소。결과32례아주원성아주아수연합병변양본중미생물감염적검출솔위46．9％，이내슬균속、봉상간균속、방선균속、만곡균속、사간균속이급기혈간균속위주。32례정상대조양본중미생물감염적검출솔위18．8％，주요위내슬균속、방선균속화만곡균속。내슬균속、봉상간균속、방선균속、사간균속화기혈간균속감염위아주원성아주아수연합병변발생적주요영향인소。결론미생물감염적충류여아주원성아주아수연합병변적발생밀절상관，림상응채취불동적치료방안이제고연합병변적치유솔、강저환자실아솔。
Objective To explore the correlation between microbial strains and infection situation of periodontal-origianted periodontal-endodontic combined lesions and related risk factors.Methods A total of 32 cases of periodontal-origianted periodontal-endodontic combined lesions and another 32 cases of normal orthodontic pulling teeth treated in Hankou Hospital from Jan.2012 to Dec.2013 were selected as research objects.Samples of periodontal pocket and root tube were collected for microbial testing,and correlation be-tween microbial contamination and the development of disease was analyzed.Results The detection rate of microbial infection in 32 cases of periodontal-origianted periodontal-endodontic combined lesions was 46.9%,the main microorganisms infected were Neisseria, Corynebacterium, Actinomyces, Campylobacter, Fusobacterium and Haemophilus.The detection rate of microbial infection in 32 cases of normal teeth was 18.8%,the main microorganisms included Neisseria,Actinomyces and Campylobacter.Neisseria,Corynebac-terium,Actinomyces,Fusobacterium and Haemophilus were the main factors that influence on the incidence of periodontal-origianted periodontal-endodontic combined lesions.Conclusion The species of microorgan-isms infected are closely related to the incidence of periodontal-origianted periodontal-endodontic combined lesions.Proper therapy should be adopted in clinic in order to improve the cure rate and reduce the rate of lost tooth.