CAJ | 학술논문

目的：探究临床淋巴结阴性cN0甲状腺微小癌的复发情况及其影响因素。方法采用自编问卷收集2008年6月至2011年6月深圳市宝安区西乡人民医院甲状腺外科收治的375例cN0甲状腺微小癌患者的临床资料，通过门诊、电话、QQ和飞信等方式完成为期3年的随访，采用描述性统计和二分类Logistic回归分析进行临床资料的分析。结果甲状腺微小癌复发率为14．4％。二分类Logistic回归分析显示，甲状腺包膜侵犯（回归系数为1．95，OR＝7．03）、中央区淋巴结未清除（回归系数为2．61，OR＝0．07）和术后未接受放射性碘治疗（回归系数为2．01，OR＝0．13）是患者复发的危险因素。结论甲状腺微小癌术后复发仍较高，其复发受多方面因素影响。如果条件允许，中央区淋巴结清除并让患者术后接受放射性碘治疗能降低患者术后复发率。
목적：탐구림상림파결음성cN0갑상선미소암적복발정황급기영향인소。방법채용자편문권수집2008년6월지2011년6월심수시보안구서향인민의원갑상선외과수치적375례cN0갑상선미소암환자적림상자료，통과문진、전화、QQ화비신등방식완성위기3년적수방，채용묘술성통계화이분류Logistic회귀분석진행림상자료적분석。결과갑상선미소암복발솔위14．4％。이분류Logistic회귀분석현시，갑상선포막침범（회귀계수위1．95，OR＝7．03）、중앙구림파결미청제（회귀계수위2．61，OR＝0．07）화술후미접수방사성전치료（회귀계수위2．01，OR＝0．13）시환자복발적위험인소。결론갑상선미소암술후복발잉교고，기복발수다방면인소영향。여과조건윤허，중앙구림파결청제병양환자술후접수방사성전치료능강저환자술후복발솔。
Objective To analyze the recurrence and influence factors of lymph node negative cN0 thy-roid microcarcinoma.Methods Clinical data of 375 cases of cN0 thyroid microcarcinoma treated in Xixiang People′s Hospital of Baoan District from Jun.2008 to Jun.2011 were collected by the self-made question-naire.A three-year follow-up were completed via outpatient,QQ,telephone and fetion services.The conclu-sion were analyzed by descriptive statistics and classified logistic regression analysis .Results The recur-rence rate of thyroid microcarcinoma was 14.4%.Logistic regression analysis found that the thyroid capsular invasion(regression coefficient=1.95,OR =7.03),not remove lymph node in central region(regression coefficient=2.61,OR=0.13) and postoperative not receive radioactive iodine therapy(regression coeffi-cient=2.01,OR=0.07) were the risk factors of the recurrence.Conclusion The postoperative recurrence rate of thyroid microcarcinoma is still high,the recurrence is influenced by many factors.If the conditions per-mit,removing lymph node in central region and applying postoperative radioactive iodine therapy can reduce recurrence probability.