CAJ | 학술논문

目的：研究罗哌卡因混合液头皮切口浸润麻醉在开颅手术中的应用。方法随机选取于2013年6月～2014年10月前来我院进行开颅手术治疗的患者共60例作为本次研究对象。随机将患者分为观察组和对照组，观察组患者切口应用1%罗哌卡因+1∶20万肾上腺素+生理盐水混合液局部浸润，对照组患者应用生理盐水手术切口浸润。结果两组患者的血流动力学变化，在 T3、T4、T5、T6时对照组动脉压（MAP）、心率(HR)、呼气末异氟醚的浓度均明显高于观察组（P ＜0.05）；而对照组拔管时间（31.1±4.9）min，明显长于观察组的（16.1±2.2）min（P ＜0.05）。结论切口浸润1%罗哌卡因混合液与全身麻醉复合的使用，能有效减轻机体的应激反应，减少全麻药的用量，维持血流动力学的稳定，值得在神经外科麻醉方面广泛推广。
목적：연구라고잡인혼합액두피절구침윤마취재개로수술중적응용。방법수궤선취우2013년6월～2014년10월전래아원진행개로수술치료적환자공60례작위본차연구대상。수궤장환자분위관찰조화대조조，관찰조환자절구응용1%라고잡인+1∶20만신상선소+생리염수혼합액국부침윤，대조조환자응용생리염수수술절구침윤。결과량조환자적혈류동역학변화，재 T3、T4、T5、T6시대조조동맥압（MAP）、심솔(HR)、호기말이불미적농도균명현고우관찰조（P ＜0.05）；이대조조발관시간（31.1±4.9）min，명현장우관찰조적（16.1±2.2）min（P ＜0.05）。결론절구침윤1%라고잡인혼합액여전신마취복합적사용，능유효감경궤체적응격반응，감소전마약적용량，유지혈류동역학적은정，치득재신경외과마취방면엄범추엄。
Objective To research the application of ropivacaine scalp incision infiltration anesthesia in craniotomy. Methods 60 patients who were admitted to our hospital and received craniotomy from June 2013 to October 2014 were selected as research subjects. They were randomly allocated to observation group and control group. The incisions of observation group were infiltrated with 1% ropivacaine, 1:200000 adrenaline and normal saline, and the incisions of control group were infiltrated with normal saline. Results Hemodynamic changes of two groups were compared, and mean artery pressure (MAP), heart rate (HR), and density of end-expiratory isoflurane at T3, T4, T5 and T6 in control group were significantly higher than those in observation group (P < 0.05) . Extubation time in control group was (31.1±4.9) min, which was significantly longer than that of observation group (16.1±2.2) min (P < 0.05). Conclusion Incision infiltrated with 1% ropivacaine mixture combined with general anesthesia can effectively alleviate stress reaction of organism, reduce general anesthetic, and maintain hemodynamic stability, which is worthy of widespread promotion in anesthetic department of neurosurgery.