CAJ | 학술논문

目的：探讨分析胸腺肽肠溶片辅助治疗寻常型银屑病的可行性。方法选取2010年8月～2012年10月来我院就诊治疗的寻常型银屑病患者72例，随机分为对照组和观察组，对照组36例患者单独口服阿维A胶囊，观察组36例患者则口服阿维A胶囊和胸腺肽肠溶片，对比两组患者的临床疗效及不良反应情况。结果观察组总治疗有效率为97.2％明显高于对照组77.7％的总治疗有效率（P ＜0.05）；而不良反应上，两组患者主要为不同程度的皮肤症状，对照组不良反应发生率69.4％，观察组不良反应发生率75.0％，差异无统计学意义（P ＞0.05）；对两组患者进行为期半年的随访，发现对照组36例患者半年内复发1例，复发率为2.8％；对照组36例患者中复发2例，复发率为5.6％，差异无统计学意义（P ＞0.05）。结论胸腺肽肠溶片是一种较好的辅助治疗药物，其辅助阿维 A 胶囊治疗寻常型银屑病具有较好的临床效果，且不增加不良反应发生率，较为安全可靠，值得临床应用。
목적：탐토분석흉선태장용편보조치료심상형은설병적가행성。방법선취2010년8월～2012년10월래아원취진치료적심상형은설병환자72례，수궤분위대조조화관찰조，대조조36례환자단독구복아유A효낭，관찰조36례환자칙구복아유A효낭화흉선태장용편，대비량조환자적림상료효급불량반응정황。결과관찰조총치료유효솔위97.2％명현고우대조조77.7％적총치료유효솔（P ＜0.05）；이불량반응상，량조환자주요위불동정도적피부증상，대조조불량반응발생솔69.4％，관찰조불량반응발생솔75.0％，차이무통계학의의（P ＞0.05）；대량조환자진행위기반년적수방，발현대조조36례환자반년내복발1례，복발솔위2.8％；대조조36례환자중복발2례，복발솔위5.6％，차이무통계학의의（P ＞0.05）。결론흉선태장용편시일충교호적보조치료약물，기보조아유 A 효낭치료심상형은설병구유교호적림상효과，차불증가불량반응발생솔，교위안전가고，치득림상응용。
Objective To analyze the feasibility of thymosin enteric-coated tablets as adjuvant therapy in treating psoriasis vulgaris. Methods 72 psoriasis vulgaris patients were selected in our hospital from August 2010 to October 2012, randomly divided into contrast group and observed group,36 patients of contrast group using avi A capsules treatment,36 patients of observed group using avi A capsules combined with thymosin enteric-coated tablets treatment,comparing the Clinical efficacy and adverse reactions of two groups. Results The total treatment efficiency of observed group was 97.2% , higher than the total treatment efficiency(77.7%) of contrast group(P < 0.05);however on the adverse reactions, patients of two groups were mainly with varying degrees of skin conditions, adverse reaction rates of contrast group being 69.4% , adverse reaction rates of the observed group being 75.0% , the difference was not statistically significant (P > 0.05); the patients of two groups were followed up six months, 36 patients of the control group were found with relapsed one case in six months, the recurrence rate being 2.8% ; 36 patients of control group with relapsed two, tthe recurrence rate being 5.6% , the difference was not statistically significant (P > 0.05). Conclusion Thymosin enteric-coated tablets is a good adjuvant therapy drug, it having a better clinical result when combined with Avi A capsule in treating psoriasis vulgaris, and does not increase the incidence of adverse reactions, more secure, reliable, worthy of clinical application.