中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
9期
90-92
,共3页
产后出血%宫缩乏力性%卡前列素氨丁三醇%临床效果
產後齣血%宮縮乏力性%卡前列素氨丁三醇%臨床效果
산후출혈%궁축핍력성%잡전렬소안정삼순%림상효과
Postpartum hemorrhage%Uterine atony%Carboprost trometamole injection%Clinical effect
目的：探讨卡前列素氨丁三醇注射液（欣母沛）治疗宫缩乏力性产后出血（PHH）的临床疗效。方法选取本院2013年1月～2014年10月接收的94例宫缩乏力性 PHH 产妇为研究对象，随机分为两组。对照组给予缩宫素、子宫按摩等常规治疗；观察组在对照组基础上给予欣母沛宫体注射，250μg/次。观察比较两组患者产后2h、产后24h 出血量。比较两组患者治疗总有效率、宫腔纱条填塞及不良反应发生率。结果产后2h，两组患者出血量比较差异无统计学意义（P ＞0.05）；给予治疗后，观察组产后24h 出血量显著低于对照组（P ＜0.05）。观察组总有效率显著高于对照组（95.7%和72.3%，x2=9.60，P=0.002)，宫腔纱条填塞发生率显著低于对照组（8.51%和40.4%，x2=12.9，P=0.000），不良反应发生率高于对照组（10.6%和6.38%），但差异无统计学意义（x2=0.547，P=0.357）。结论欣母沛能够有效减少宫缩乏力性 PHH 患者的出血量，疗效确切、安全性高，值得在临床上推广应用。
目的：探討卡前列素氨丁三醇註射液（訢母沛）治療宮縮乏力性產後齣血（PHH）的臨床療效。方法選取本院2013年1月～2014年10月接收的94例宮縮乏力性 PHH 產婦為研究對象，隨機分為兩組。對照組給予縮宮素、子宮按摩等常規治療；觀察組在對照組基礎上給予訢母沛宮體註射，250μg/次。觀察比較兩組患者產後2h、產後24h 齣血量。比較兩組患者治療總有效率、宮腔紗條填塞及不良反應髮生率。結果產後2h，兩組患者齣血量比較差異無統計學意義（P ＞0.05）；給予治療後，觀察組產後24h 齣血量顯著低于對照組（P ＜0.05）。觀察組總有效率顯著高于對照組（95.7%和72.3%，x2=9.60，P=0.002)，宮腔紗條填塞髮生率顯著低于對照組（8.51%和40.4%，x2=12.9，P=0.000），不良反應髮生率高于對照組（10.6%和6.38%），但差異無統計學意義（x2=0.547，P=0.357）。結論訢母沛能夠有效減少宮縮乏力性 PHH 患者的齣血量，療效確切、安全性高，值得在臨床上推廣應用。
목적：탐토잡전렬소안정삼순주사액（흔모패）치료궁축핍력성산후출혈（PHH）적림상료효。방법선취본원2013년1월～2014년10월접수적94례궁축핍력성 PHH 산부위연구대상，수궤분위량조。대조조급여축궁소、자궁안마등상규치료；관찰조재대조조기출상급여흔모패궁체주사，250μg/차。관찰비교량조환자산후2h、산후24h 출혈량。비교량조환자치료총유효솔、궁강사조전새급불량반응발생솔。결과산후2h，량조환자출혈량비교차이무통계학의의（P ＞0.05）；급여치료후，관찰조산후24h 출혈량현저저우대조조（P ＜0.05）。관찰조총유효솔현저고우대조조（95.7%화72.3%，x2=9.60，P=0.002)，궁강사조전새발생솔현저저우대조조（8.51%화40.4%，x2=12.9，P=0.000），불량반응발생솔고우대조조（10.6%화6.38%），단차이무통계학의의（x2=0.547，P=0.357）。결론흔모패능구유효감소궁축핍력성 PHH 환자적출혈량，료효학절、안전성고，치득재림상상추엄응용。
Objective To investigate the curative effect of carboprost Trometamole Injection (hemabate) in treatment of postpartum hemorrhage caused by uterine inertia (PHH). Methods 94 cases of uterine atony of maternal PHH admitted in our hospital from January 2013 to October 2014 were select as the research object and were divided into the control group and the observation group according to the drawing method of random sampling.The patients in the control group were give noxytocin,kneading uterine and other conventional treatment while the patients in the observation group were given hemabate injection250ug/times,based on of the treatment of the control group.The amount of postpartum hemorrhage of the patients in the two groups of patients was compared after two hours and twenty four hours of birth.The total effective rate,incidence of intrauterine packing with gauze and adverse reaction of the patients in two groups were compared. Results Two hours of the birth,the amount of postpartum hemorrhage of the patients in two groups had no difference significant (P > 0.05) but after the treatment, the amount of postpartum hemorrhage of the patients in the observation group was significantly lower than that of the control group (P < 0.05) twenty four hours after birth.The total effective rate in the observation group was significantly higher than that in control group (95.7%VS72.3%,x2=9.60,P=0.002),The incidence of intrauterine packing with gauze was significantly lower than that of the control group (8.51%VS40.4%,x2=12.9,P=0.000).The incidence of adverse reactions in the observation group was higher than that of the control group (10.6% VS 6.38%),but the difference was not statistically significant (x2=0.547,P=0.357). Conclusion Hemabate can effectively reduce bleeding caused by uterine atony in PHH patients and curative effect is good and safe,which is worth clinical application.
