中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2015年
10期
192-194
,共3页
李雯霖%何爱群%卓晓%林海波%陈慕丹
李雯霖%何愛群%卓曉%林海波%陳慕丹
리문림%하애군%탁효%림해파%진모단
碱性成纤维细胞生长因子%转化生长因子 β%病理性近视
堿性成纖維細胞生長因子%轉化生長因子 β%病理性近視
감성성섬유세포생장인자%전화생장인자 β%병이성근시
Basic fibroblast growth factor(bFGF )%Transforming growth factor-β(TGF-β)%Pathological myopia
目的:探讨病理性近视患者 bFGF 和 TGF-β的表达水平。方法对我院门诊就诊的病理性近视患者、非病理性近视患者和正常对照组的 bFGF 和 TGF-β的表达水平进行检测,探讨其在病理性近视患者和非病理性近视患者中的表达强度。结果与正常对照组比较,病理性近视和非病理性近视患者血中bFGF 表达明显低于正常对照组,而这两组患者血中 TGF-β的表达明显高于正常对照组,差异具有统计学意义(P <0.01)。结论 bFGF 和 TCF-β可能在病理性近视的发生发展过程序中发挥着一定的作用。
目的:探討病理性近視患者 bFGF 和 TGF-β的錶達水平。方法對我院門診就診的病理性近視患者、非病理性近視患者和正常對照組的 bFGF 和 TGF-β的錶達水平進行檢測,探討其在病理性近視患者和非病理性近視患者中的錶達彊度。結果與正常對照組比較,病理性近視和非病理性近視患者血中bFGF 錶達明顯低于正常對照組,而這兩組患者血中 TGF-β的錶達明顯高于正常對照組,差異具有統計學意義(P <0.01)。結論 bFGF 和 TCF-β可能在病理性近視的髮生髮展過程序中髮揮著一定的作用。
목적:탐토병이성근시환자 bFGF 화 TGF-β적표체수평。방법대아원문진취진적병이성근시환자、비병이성근시환자화정상대조조적 bFGF 화 TGF-β적표체수평진행검측,탐토기재병이성근시환자화비병이성근시환자중적표체강도。결과여정상대조조비교,병이성근시화비병이성근시환자혈중bFGF 표체명현저우정상대조조,이저량조환자혈중 TGF-β적표체명현고우정상대조조,차이구유통계학의의(P <0.01)。결론 bFGF 화 TCF-β가능재병이성근시적발생발전과정서중발휘착일정적작용。
Objective To explore the expression of bFGF and TGF-β and the relationship with pathological myopia. Methods The level of bFGF and TGF-β were detected in patients with pathological myopia and non-pathological myopia and healthy controls. Results The expression level of bFGF were lower in patients with pathological myopia than non-pathological myopia andhealthy controls,and the expression level of TGF-β were higher in patients with pathological myopia than non-pathological myopia and healthy controls,the difference was significant(P < 0.01). Conclusion Conclusion bFGF and TGF-β may play a certain role in the occurrence and development of pathological myopia.