CAJ | 학술논문

目的：评价地诺前列酮与双球囊导管用于促宫颈成熟的临床疗效和安全性。方法将208名Bishop评分≤6的产妇随机分为试验组105例和对照组103例。试验组用双球囊导管促宫颈成熟，对照组将1枚地诺前列酮10 mg置于阴道穹窿的深处用于促宫颈成熟。记录在24 h内分娩的相关数据，比较2组的临床疗效和不良反应发生率。结果试验组24 h内经阴道分娩成功的比例较对照组高（68.57％vs 49.51％，P＜0.05）。剖宫产率在2组间差异无统计学意义（23.81％vs 26.21％，P＞0.05）。试验组催产素和硬膜外镇痛的使用率较对照组高（ P ＜0.05），而对照组子宫张力过大和宫缩过频发生率较试验组高（ P＜0.05）。结论双球囊导管用于促宫颈成熟较地诺前列酮可以增加24 h内阴道分娩成功率。
목적：평개지낙전렬동여쌍구낭도관용우촉궁경성숙적림상료효화안전성。방법장208명Bishop평분≤6적산부수궤분위시험조105례화대조조103례。시험조용쌍구낭도관촉궁경성숙，대조조장1매지낙전렬동10 mg치우음도궁륭적심처용우촉궁경성숙。기록재24 h내분면적상관수거，비교2조적림상료효화불량반응발생솔。결과시험조24 h내경음도분면성공적비례교대조조고（68.57％vs 49.51％，P＜0.05）。부궁산솔재2조간차이무통계학의의（23.81％vs 26.21％，P＞0.05）。시험조최산소화경막외진통적사용솔교대조조고（ P ＜0.05），이대조조자궁장력과대화궁축과빈발생솔교시험조고（ P＜0.05）。결론쌍구낭도관용우촉궁경성숙교지낙전렬동가이증가24 h내음도분면성공솔。
Objective To evaluation the clinical efficacy and safety of dinoprostone and double balloon catheter for cervical ripening . Methods A total of 208 women with Bishop score less than 6 were ran-domly divided into treatment group ( n =105 ) and control group ( n =103).Patients in treatment group were given double balloon catheter for cervical ripening , and patients in control group were given dinoprostone for cervical ripening.The data of vaginal delivery in 24 hours, clinical efficacy and incidence of adverse drug reactions were recorded and com-pared between the two groups.Results The proportion of women who a-chieved vaginal delivery in 24 hours was higher in the treatment group than in the control group (68.57% vs 49.51%,P<0.05).There was no difference in cesarean delivery rates between the two groups ( 23.81%vs 26.21%, P>0.05 ) .Oxytocin and epidural analgesia were adminis-tered more frequently in treatment group (P<0.05).Uterine tachysystole or hypertonus occurred more frequently in the control group ( P<0.05 ) . Conclusion Double-balloon catheter can improve the for vaginal birth within 24 hours in the treatment of cervical ripening .