CAJ | 학술논문

目的：观察复方玄驹胶囊治疗男性不育患者核蛋白组型转换和顶体酶活性和精子相关参数的疗效。方法对35例精液核蛋白组型转换和顶体酶活性异常男性不育患者采用复方玄驹胶囊治疗，3个月为1个疗程；统计分析治疗前后核蛋白组型转换和顶体酶活性、精子相关参数的变化情况。结果纳入统计的31例患者治疗后精子密度显著增加（P ＜0．05），精子前向活力和精子总活力明显改善（P ＜0．05），核蛋白组型转换和顶体酶活性明显增强（P ＜0．01）。结论复方玄驹胶囊可显著提升精子核蛋白组型转换和顶体酶活性及精子相关参数，改善精子质量。
목적：관찰복방현구효낭치료남성불육환자핵단백조형전환화정체매활성화정자상관삼수적료효。방법대35례정액핵단백조형전환화정체매활성이상남성불육환자채용복방현구효낭치료，3개월위1개료정；통계분석치료전후핵단백조형전환화정체매활성、정자상관삼수적변화정황。결과납입통계적31례환자치료후정자밀도현저증가（P ＜0．05），정자전향활력화정자총활력명현개선（P ＜0．05），핵단백조형전환화정체매활성명현증강（P ＜0．01）。결론복방현구효낭가현저제승정자핵단백조형전환화정체매활성급정자상관삼수，개선정자질량。
Objective To study the ef icacy of“Huangjing Zanyu Cap sule”in the treatment of male infertility due to abnormal sperm -nucleoprotein transition and acrosin.Methods Thirty five subjects were treated with“Xuanju Compound Capsule”for three months;the activity of acrosin and semen dynamics were observed before and after the treatment.Results After 3 months treatments,thirty one subjects were included in The statistics .The activity of semen density,anteriad vitality and total vitality were obviously improved (P <0.05),sperm -nucleoprotein transition and arcrosin were obviously ameliorated (P <0.01).Conclusion “Xuanju Compound Capsule”can obviously improve sperm -nucleoprotein transition and acrosin activity and semen quality.