CAJ | 학술논문

目的：主要对质量分析器的研究进展作一综述，另外还对新型质量分析器的发展趋势进行展望。方法以近年来国内外发表的文献为依据，并结合一些药物对新型质量分析器做了介绍。结果与结论质谱是一种与光谱并列的谱学方法，其在一次分析中可提供丰富的结构信息，并具备高特异性和高灵敏度，将分离技术与质谱法相结合是分离科学方法中的一项突破性进展。质谱仪器一般由离子源、质量分析器、检测器等部分组成，而质量分析器是最核心的部件，位于离子源和检测器之间，依据不同方式将离子源中生成的样品离子按质荷比 m ／z 的大小分开。
목적：주요대질량분석기적연구진전작일종술，령외환대신형질량분석기적발전추세진행전망。방법이근년래국내외발표적문헌위의거，병결합일사약물대신형질량분석기주료개소。결과여결론질보시일충여광보병렬적보학방법，기재일차분석중가제공봉부적결구신식，병구비고특이성화고령민도，장분리기술여질보법상결합시분리과학방법중적일항돌파성진전。질보의기일반유리자원、질량분석기、검측기등부분조성，이질량분석기시최핵심적부건，위우리자원화검측기지간，의거불동방식장리자원중생성적양품리자안질하비 m ／z 적대소분개。
OBJECTIVE Research progress of mass analyzer was briefly reviewed in this paper,in addition,the development trend of novel mass analyzer were discussed.METHODS Some newly developed mass analyzer were summaried according to recent references and some drugs.RESULTS AND CONCLUSION Mass spectrometry coordinated with spectroscopy,can pro-vide abundant structural information in one analysis,and has high specificity and high sensitivity.Therefore,combining the separation technology and mass spectrometry is a breakthrough of the separation scientific method.In general,a mass spectrometer consists of an ion source,a mass analyzer and a detector which are operated under high vacuum conditions.However,mass analy-zer,between the ion source and detector,is one of the most core components.And the analyzer depending on dif erent modes can separate various ions which are generated by the ion source by their mass -to -charge ratio(m /z).