CAJ | 학술논문

目的：分析恶性肿瘤诊疗中血液流变学检验的应用价值。方法100例该院肿瘤外科确诊的恶性肿瘤患者纳入研究组，根据有无远处转移分为有远处转移亚组和无远处转移亚组，50例体检健康者纳入对照组，比较各组的血液流变学检验结果。结果有远处转移的患者其全血黏度、红细胞聚集指数、纤维蛋白原水平均明显高于无远处转移的患者，其红细胞压积明显低于无远处转移的患者，差异均有统计学意义（P＜0．05）。有远处转移的恶性肿瘤患者其各项血液流变学指标均与对照组比较，差异均有统计学意义（P＜0．05），无远处转移的恶性肿瘤患者其各项血液流变学指标除红细胞聚集指数外，与对照组差异均有统计学意义（P＜0．05）。治疗后恶性肿瘤患者的全血黏度、血浆黏度、红细胞压积3指标水平均较治疗前有明显改善，治疗前后差异有统计学意义（P＜0．05）。结论恶性肿瘤的诊疗过程中，血液流变学的检验指标在随着病情的进展和改善不断发生变化，其参数的检测有着重要的应用价值。
목적：분석악성종류진료중혈액류변학검험적응용개치。방법100례해원종류외과학진적악성종류환자납입연구조，근거유무원처전이분위유원처전이아조화무원처전이아조，50례체검건강자납입대조조，비교각조적혈액류변학검험결과。결과유원처전이적환자기전혈점도、홍세포취집지수、섬유단백원수평균명현고우무원처전이적환자，기홍세포압적명현저우무원처전이적환자，차이균유통계학의의（P＜0．05）。유원처전이적악성종류환자기각항혈액류변학지표균여대조조비교，차이균유통계학의의（P＜0．05），무원처전이적악성종류환자기각항혈액류변학지표제홍세포취집지수외，여대조조차이균유통계학의의（P＜0．05）。치료후악성종류환자적전혈점도、혈장점도、홍세포압적3지표수평균교치료전유명현개선，치료전후차이유통계학의의（P＜0．05）。결론악성종류적진료과정중，혈액류변학적검험지표재수착병정적진전화개선불단발생변화，기삼수적검측유착중요적응용개치。
Objective To explore the value of the application of hemorheology test in diagnosis and treatment of malignant tumor .Methods A total of 100 patients suffered from malignant tumors selected as study group ,and divided as distant metastasis subgroup and no distant metastasis subgroup ,meanwhile 50 healthy persons were selected into control group .Test results of hemo‐rheology were compared .Results The whole blood viscosity ,erythrocyte aggregation index ,fibrinogen levels in the distant metasta‐sis subgroup were significant higher than those of the no distant metastasis group ,and the hematokrit level was significant lower than that of the no distant metastasis group ,the differences were statistical significant(P< 0 .05) .The parameters of hemorheology in the distant metastasis subgroup were significant different with that of the control group(P< 0 .05) .Except for erythrocyte aggre‐gation index ,other parameters of hemorheology were also significant different with those of the control group(P < 0 .05) .After treatment the whole blood viscosity ,packed cell volume and plasma viscosity had improved significantly comparing with before treatment(P< 0 .05) .Conclusion In the process of diagnosis and treatment of malignant tumors ,test indicators in hemorheology are constantly changing with the progress of the disease ,which has important application value .