CAJ | 학술논문

目的：了解该地区 RhD 阴性献血者表型分布，建立 RhD 阴性表型数据库。方法 RhD 初筛阴性的554份标本采用间接抗球蛋白试验确认。排除重复献血者后，剩余标本为366份，对其进行 Rh 血型表型分析。结果 RhD 阴性表型分布特征为ccdee（56．28％）＞ Ccdee （29．51％）＞ ccdEe （7．38％）＞ CcdEe （3．55％）＞ CCdee （3．01％）＞ ccdEE （0．27％），未检出 CcdEE 、CCdEe 、CCdEE 型。结论建立 RhD 阴性表型数据库，有利于为 RhD 阴性及含有 Rh 同种抗体的患者提供相匹配血液，满足其急救用血，且对科学管理 RhD 阴性血源和合理运用 RhD 阴性血液有重要意义，为该地区尤其蒙古族 RhD 阴性血型积累了资料。
목적：료해해지구 RhD 음성헌혈자표형분포，건립 RhD 음성표형수거고。방법 RhD 초사음성적554빈표본채용간접항구단백시험학인。배제중복헌혈자후，잉여표본위366빈，대기진행 Rh 혈형표형분석。결과 RhD 음성표형분포특정위ccdee（56．28％）＞ Ccdee （29．51％）＞ ccdEe （7．38％）＞ CcdEe （3．55％）＞ CCdee （3．01％）＞ ccdEE （0．27％），미검출 CcdEE 、CCdEe 、CCdEE 형。결론건립 RhD 음성표형수거고，유리우위 RhD 음성급함유 Rh 동충항체적환자제공상필배혈액，만족기급구용혈，차대과학관리 RhD 음성혈원화합리운용 RhD 음성혈액유중요의의，위해지구우기몽고족 RhD 음성혈형적루료자료。
Objective To understand the phenotype distribution of negative RhD blood donors in local region ,and to establish negative RhD phenotype database .Methods A total of 554 specimens screened firstly as negative RhD were confirmed by indirect antiglobulin test .Repeat donors were excluded ,the remaining specimens were 366 cases ,which were analyzed the phenotype of Rh blood .Results Distribution characteristics of negative RhD phenotype was ccdee (56 .28% ) > Ccdee (29 .51% ) > ccdEe (7 .38% )> CcdEe (3 .55% )> CCdee (3 .01% )> ccdEE (0 .27% ) ,there were no CcdEE ,CCdEe ,CCdEE detected .Conclusion The establishment of Negative RhD phenotype database is help for providing matching blood for persons with negative RhD blood or same antibody blood ,and meeting the emergency blood usage ,it′s important for scientific management and reasonable application of negative RhD blood ,and accumulate data for then negative RhD blood of the local area ,especially for Mongolian .