CAJ | 학술논문

目的：了解溶血葡萄球菌的耐药性，为临床合理用药作出指导。方法从患者标本中分离出59株溶血葡萄球菌，并对其进行临床分布及耐药性分析。结果59株溶血葡萄球菌主要集中于儿科与 ICU 等科室，标本主要来源于痰液和咽拭子，患者以新生儿为主；溶血葡萄球菌以耐甲氧西林溶血葡萄球菌（MRSH）为主，共53株，占89．8％；耐甲氧西林溶血葡萄球菌（MR‐SH）对多种抗菌药物呈高度多重耐药，而对万古霉素、替考拉宁、利奈唑胺敏感率高，为100．0％。结论溶血葡萄球菌是临床感染的重要的凝固酶阴性葡萄球菌之一，其以 MRSH 为主，且呈高度多重耐药，临床上应根据其药敏试验结果合理选用抗菌药物。
목적：료해용혈포도구균적내약성，위림상합리용약작출지도。방법종환자표본중분리출59주용혈포도구균，병대기진행림상분포급내약성분석。결과59주용혈포도구균주요집중우인과여 ICU 등과실，표본주요래원우담액화인식자，환자이신생인위주；용혈포도구균이내갑양서림용혈포도구균（MRSH）위주，공53주，점89．8％；내갑양서림용혈포도구균（MR‐SH）대다충항균약물정고도다중내약，이대만고매소、체고랍저、리내서알민감솔고，위100．0％。결론용혈포도구균시림상감염적중요적응고매음성포도구균지일，기이 MRSH 위주，차정고도다중내약，림상상응근거기약민시험결과합리선용항균약물。
Objective To investigate the drug resistance of Staphylococcus haemolyticus and provide basis for selection of clini‐cal drugs .Methods A total of 59 strains of Staphylococcus haemolyticus were isolated from patients ,and analyzed the clinical dis‐tribution and drug resistance of them .Results Staphylococcus haemolyticus were mainly isolated from the sputum and oropharyn‐geal swabs in pediatric and ICU .The patients were mainly newborns .Staphylococcus haemolyticus mainly included methicillin re‐sistant Staphylococcus haemolyticus (MRSH) ,accounting for 89 .8% (53 strains) .MRSH showed high‐drug resistance and multi‐drug resistance .However ,it was sensitive to vancomycin ,teicoplanin and linezolid ,the antibiotic sensitive rate was 100 .0% .Conclu‐sion Staphylococcus haemolyticus is an important coagulase negative staphylococci ,mainly including MRSH ,which shows high‐drug resistance and multi‐drug resistance .