CAJ | 학술논문

目的：：分析酒石酸美托洛尔治疗扩张型心肌病的临床治疗效果。方法：选取78例扩张型心肌病患者,随机分为对照组和观察组,每组各39例。对照组患者接受常规抗心律失常治疗,观察组患者在常规治疗基础上辅以酒石酸美托洛尔治疗。对比分析两组患者治疗前后心率(HR)、24 h 尿量、左室射血分数(LVEF)和临床疗效的差异性。结果：与治疗前比较,经过治疗后患者 HR 有所下降,24 h 尿量、LVEF 有所增加,其中观察组患者各指标改善幅度明显大于对照组,两组间差异有统计学意义(P<0.05)；观察组患者总有效率明显高于对照组,两组间差异有统计学意义(P<0.05)。结论：在扩张型心肌病治疗期间辅以β受体阻滞剂酒石酸美托洛尔治疗,可有效改善心功能,对患者的预后有益。
목적：：분석주석산미탁락이치료확장형심기병적림상치료효과。방법：선취78례확장형심기병환자,수궤분위대조조화관찰조,매조각39례。대조조환자접수상규항심률실상치료,관찰조환자재상규치료기출상보이주석산미탁락이치료。대비분석량조환자치료전후심솔(HR)、24 h 뇨량、좌실사혈분수(LVEF)화림상료효적차이성。결과：여치료전비교,경과치료후환자 HR 유소하강,24 h 뇨량、LVEF 유소증가,기중관찰조환자각지표개선폭도명현대우대조조,량조간차이유통계학의의(P<0.05)；관찰조환자총유효솔명현고우대조조,량조간차이유통계학의의(P<0.05)。결론：재확장형심기병치료기간보이β수체조체제주석산미탁락이치료,가유효개선심공능,대환자적예후유익。
Objective: To analyze clinical treatment effects and status of patients with dilated cardiomyopathy (DCM). Meth-ods: 78 cases patients with DCM were randomly divided into observation group and control group, 39 cases in each group. The control group patients received routine anti-arrhythmic treatment; while on the basis of conventional treatment, the observation group patients were given tartaric acid metoprolol tartrate therapy. A contrastive analysis of the two groups before and after the treatment in heart rate (HR), 24 h urine, left ventricular ejection fraction (LVEF) and the clinical curative effects was performed. Results: Compared with those before the treatment, the HR declined, 24 h urine and LVEF increased after the treatment. The index improvement of observation group was significantly greater than that of control group, and t test analysis found that the difference between the two groups was statis-tically significant (P<0. 05). The total effective rate of observation group was significantly higher than that of control group, and chi-square analysis found that the difference between the two groups was statistically significant ( P<0. 05). Conclusions: During the treatment with beta-blockers in DCN, metoprolol tartrate therapy added can effectively improve cardiac function, and is beneficial to the prognosis of the patients.