医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2015年
5期
1-1
,共1页
康莱特注射液%非小细胞肺癌%化疗%毒副反应
康萊特註射液%非小細胞肺癌%化療%毒副反應
강래특주사액%비소세포폐암%화료%독부반응
Kanglaite injection%non smal cel lung cancer%chemotherapy%toxicity
目的：探讨康莱特注射液联合化疗治疗晚期非小细胞肺癌的临床疗效，为晚期非小细胞肺癌的治疗提供有效参考。方法：选取我院2012年8月～2015年1月收治的晚期非小细胞肺癌患者108例为研究对象，按照1：1比例分为对照组与观察组，各54例，2组患者均给予常规化疗治疗，观察组加用康莱特注射液联合化疗治疗，疗程结束后比较2组临床疗效及毒副反应发生情况。结果：观察组有效率为57．41％明显高于对照组33．33％（P ＜0．05）；观察组中医症候改善率为62．96％明显高于对照组的37．04％（P ＜0．05）；且毒副反应结果显示，观察组白细胞降低及胃肠道反应发生率低于对照组，差异有统计学意义（P ＜0．05）。与治疗前比较，观察组 CD3、CD4、CD8、CD4／CD8及 NKT 细胞活性均无显著差异（P ＞0．05）；对照组与治疗前比较 CD3、CD4、CD4／CD8及 NKT 细胞活性显著下降（P ＜0．05）。结论：康莱特注射液配合化疗可减轻化疗毒副反应，提高患者化疗耐受性，值得在晚期非小细胞肺癌治疗中推广和应用。
目的：探討康萊特註射液聯閤化療治療晚期非小細胞肺癌的臨床療效，為晚期非小細胞肺癌的治療提供有效參攷。方法：選取我院2012年8月～2015年1月收治的晚期非小細胞肺癌患者108例為研究對象，按照1：1比例分為對照組與觀察組，各54例，2組患者均給予常規化療治療，觀察組加用康萊特註射液聯閤化療治療，療程結束後比較2組臨床療效及毒副反應髮生情況。結果：觀察組有效率為57．41％明顯高于對照組33．33％（P ＜0．05）；觀察組中醫癥候改善率為62．96％明顯高于對照組的37．04％（P ＜0．05）；且毒副反應結果顯示，觀察組白細胞降低及胃腸道反應髮生率低于對照組，差異有統計學意義（P ＜0．05）。與治療前比較，觀察組 CD3、CD4、CD8、CD4／CD8及 NKT 細胞活性均無顯著差異（P ＞0．05）；對照組與治療前比較 CD3、CD4、CD4／CD8及 NKT 細胞活性顯著下降（P ＜0．05）。結論：康萊特註射液配閤化療可減輕化療毒副反應，提高患者化療耐受性，值得在晚期非小細胞肺癌治療中推廣和應用。
목적：탐토강래특주사액연합화료치료만기비소세포폐암적림상료효，위만기비소세포폐암적치료제공유효삼고。방법：선취아원2012년8월～2015년1월수치적만기비소세포폐암환자108례위연구대상，안조1：1비례분위대조조여관찰조，각54례，2조환자균급여상규화료치료，관찰조가용강래특주사액연합화료치료，료정결속후비교2조림상료효급독부반응발생정황。결과：관찰조유효솔위57．41％명현고우대조조33．33％（P ＜0．05）；관찰조중의증후개선솔위62．96％명현고우대조조적37．04％（P ＜0．05）；차독부반응결과현시，관찰조백세포강저급위장도반응발생솔저우대조조，차이유통계학의의（P ＜0．05）。여치료전비교，관찰조 CD3、CD4、CD8、CD4／CD8급 NKT 세포활성균무현저차이（P ＞0．05）；대조조여치료전비교 CD3、CD4、CD4／CD8급 NKT 세포활성현저하강（P ＜0．05）。결론：강래특주사액배합화료가감경화료독부반응，제고환자화료내수성，치득재만기비소세포폐암치료중추엄화응용。
Objective:To investigate the clinical ef ect of Kanglaite injection combined with chemotherapy in treatment of advanced non -smal cel lung cancer,to provide ef ectiverefer-ence for the treatment of advanced non -smal cel lung cancer.Methods:in our hospital from 2012 August to 2015 January were treated patients with advanced non -smal cel lung cancer in 108 cases as the research object,according to the proportion of 1:1 divided into control group and observation group,54 cases each,2 groups of patients were givenconventional chemotherapy treatment,the observation group added Kanglaite Injectioncombined with chemotherapy treatment,after the end of treatment and comparison adverse reaction of 2 groups of clinical curative ef ects occurred.Results:the observation group was 57.41% significantly higher than 33.33% in the control group (P <0.05);observation group symptom improvement rate was 62.96% signifi-cantly higher than 37.04% in the control group(P <0.05);and the toxicity results showed that the observation group,leukopenia and gastrointestinal reaction rate lower than the control group, there was statistical significancethe dif erence (P <0.05).Compared with before treatment,the observation group CD3,CD4,CD8,CD4 /CD8 and NKT cel s showed no significant dif erence (P >0.05);the control groupcompared with before treatment,CD3,CD4,CD4 /CD8 and NKT cel activity decreased significantly (P <0.05).Conclusion:Kanglaite injection combined with chemotherapy can reduce the side ef ects of chemotherapy,improve the patients'tolerance to chemotherapy and is worthy of popularization and application in advanced non smal cel lung cancer.
