CAJ | 학술논문

目的：探讨地塞米松灌肠联合纳米银痔疮净治疗远段溃疡性结肠炎的临床疗效和安全性。方法选择40例符合轻、中度远段溃疡性结肠炎诊断的患者随机分为观察组和对照组，每组各20例，观察组采用地塞米松灌肠联合纳米银痔疮净治疗，对照组采用柳氮磺吡啶口服治疗，比较两组的疗效和主要临床症状腹痛、腹泻、脓血便消失时间。结果观察组有效率为90％，对照组有效率为60％，两组间比较差异具有统计学意义（P ＜0．05）。观察组主要临床症状腹痛、腹泻、脓血便消失时间明显短于对照组，差异具有统计学意义（P ＜0．05）。结论地塞米松灌肠联合纳米银痔疮净治疗远段溃疡性结肠炎疗效良好，患者主要临床症状消失时间明显缩短，更快地减轻患者痛苦，提高生活质量，值得在临床上推广。
목적：탐토지새미송관장연합납미은치창정치료원단궤양성결장염적림상료효화안전성。방법선택40례부합경、중도원단궤양성결장염진단적환자수궤분위관찰조화대조조，매조각20례，관찰조채용지새미송관장연합납미은치창정치료，대조조채용류담광필정구복치료，비교량조적료효화주요림상증상복통、복사、농혈편소실시간。결과관찰조유효솔위90％，대조조유효솔위60％，량조간비교차이구유통계학의의（P ＜0．05）。관찰조주요림상증상복통、복사、농혈편소실시간명현단우대조조，차이구유통계학의의（P ＜0．05）。결론지새미송관장연합납미은치창정치료원단궤양성결장염료효량호，환자주요림상증상소실시간명현축단，경쾌지감경환자통고，제고생활질량，치득재림상상추엄。
Objective To investigate the ef icacy and safety of dexamethasone enema and nano silver gel in treatment of patients with distal ulcerative colitis.Methods A total of 40 patients were included in this study,al the patients were randomly divided into treatment and control groups.Treatment group were treated with dexamethasone enema and nano silver gel,control group were treated withsulfasalazine.Ef icacy and time of symptoms disappearred were observed.Results The total ef ective rate of treatment group was 90.0%,the control group was 60.0%,the dif er-ences between the two groups were significant(P <0.05);The time of abdominal pain,diarrhea and bloody purulent stool disappearred in treatment group was significantly shorter than the con-trol group(P <0.05).Conclusion Curative ef ect of dexamethasone enema and nano silver gel in treatment of patients with distal ulcerative colitis was good,it al eviated the suf ering of patients and improved quality of life,deserve the clinical expansion.