CAJ | 학술논문

目的：观察临床应用阿奇霉素联合盐酸氨溴索治疗小儿哮喘的疗效。方法将我院2014年5月～2015年3月诊治的50例小儿哮喘患儿随机分为药物联合组和药物单用组，药物单用组给予阿奇霉素，药物联合组给予阿奇霉素联合盐酸氨溴索治疗，观察两组患儿的治疗效果、症状消失时间和不良反应发生情况。结果药物联合组患儿治疗总有效率高于药物单用组（P<0.05）。药物联合组患儿临床症状消失时间短于药物单用组（P<0.05）。药物联合组患儿不良反应发生率与药物单用组患儿不良反应发生率差异无统计学意义（P>0.05）。结论盐酸氨溴索联合阿奇霉素治疗小儿哮喘的临床效果确切，患者临床症状消失快，不会带来严重副反应。
목적：관찰림상응용아기매소연합염산안추색치료소인효천적료효。방법장아원2014년5월～2015년3월진치적50례소인효천환인수궤분위약물연합조화약물단용조，약물단용조급여아기매소，약물연합조급여아기매소연합염산안추색치료，관찰량조환인적치료효과、증상소실시간화불량반응발생정황。결과약물연합조환인치료총유효솔고우약물단용조（P<0.05）。약물연합조환인림상증상소실시간단우약물단용조（P<0.05）。약물연합조환인불량반응발생솔여약물단용조환인불량반응발생솔차이무통계학의의（P>0.05）。결론염산안추색연합아기매소치료소인효천적림상효과학절，환자림상증상소실쾌，불회대래엄중부반응。
Objective To investigate the ef icacy of ambroxol hydrochloride combine with azithromycin in treatment of asthma in children. Methods 50 cases of pediatric asthma from May 2014 to March 2015 in our hospital were selected for research subject. The patients were randomly divided into combine groups and single drug group. The single drug group was received azithromycin drug while combination group was received ambroxol hydrochloride therapy. The therapeutic ef ects, symptom disappearance time and adverse reaction of two groups were observed. Results The total ef ective rate of combined group was significantly higher than that of single drug group(P<0.05). The symptom disappearance time of combination group was shorter than that of single drug group(P<0.05). The rate of adverse reaction of combination group had no significant dif erence with single drug group(P>0.05). Conclusion Ambroxol hydrochloride combined with azithromycin in treatment of pediatric asthma has exact ef ect. The clinical symptoms of the patients are disappeared quickly. There are no serious side ef ects.