中国麻风皮肤病杂志
中國痳風皮膚病雜誌
중국마풍피부병잡지
CHINA JOURNAL OF LEPROSY AND SKIN DISEASES
2015年
6期
331-334
,共4页
李春晓%顾艳%凌波%余红%姚志荣
李春曉%顧豔%凌波%餘紅%姚誌榮
리춘효%고염%릉파%여홍%요지영
皮肤幼年性黄色肉芽肿%病理特点%免疫组化
皮膚幼年性黃色肉芽腫%病理特點%免疫組化
피부유년성황색육아종%병리특점%면역조화
juvenile xanthogranuloma%histological features%immunohistochemistry
本文报道204例幼年性黄色肉芽肿患者,男女比例为1.65∶1,约5.88%的患者出生时即有皮损,28.43%的患者于1岁以内发病,72.06%于5岁以内发病。单发皮损患者占73.53%。根据患者的皮损组织学特点可将其分为4种病理类型:早期幼年性黄色肉芽肿(24.51%)、经典型幼年性黄色肉芽肿(47.06%)、移行幼年性黄色肉芽肿(16.18%)和混合型幼年性黄色肉芽肿(n=25,12.25%)。免疫组化的皮损组织结果均为:CD68(+)、CD1a(-)及S-100(-)。治疗上主要采取手术切除。
本文報道204例幼年性黃色肉芽腫患者,男女比例為1.65∶1,約5.88%的患者齣生時即有皮損,28.43%的患者于1歲以內髮病,72.06%于5歲以內髮病。單髮皮損患者佔73.53%。根據患者的皮損組織學特點可將其分為4種病理類型:早期幼年性黃色肉芽腫(24.51%)、經典型幼年性黃色肉芽腫(47.06%)、移行幼年性黃色肉芽腫(16.18%)和混閤型幼年性黃色肉芽腫(n=25,12.25%)。免疫組化的皮損組織結果均為:CD68(+)、CD1a(-)及S-100(-)。治療上主要採取手術切除。
본문보도204례유년성황색육아종환자,남녀비례위1.65∶1,약5.88%적환자출생시즉유피손,28.43%적환자우1세이내발병,72.06%우5세이내발병。단발피손환자점73.53%。근거환자적피손조직학특점가장기분위4충병리류형:조기유년성황색육아종(24.51%)、경전형유년성황색육아종(47.06%)、이행유년성황색육아종(16.18%)화혼합형유년성황색육아종(n=25,12.25%)。면역조화적피손조직결과균위:CD68(+)、CD1a(-)급S-100(-)。치료상주요채취수술절제。
The clinical data of two hundred and four patients with juvenile xanthogranuloma (JXG) was analyzed. The ratio of male to female was 1. 65:1. 5. 88% of the patients presented with the lesions at birth. The lesions appeared before 1 year old in 28.43% of the patients and before 5 years old in 72.06% of the pa-tients. 73.53% of the patients had one single lesion. According the histological features of the lesions, JXG was classified into four subtypes in those patients: early JXG ( 24. 51%) , classical JXG ( 47. 06%) , transi-tional JXG (16.18%) and mixed JXG (12.25%). Immunohistochemistry showed positive of CD68, negative of CD1a and S-100. Surgical excision are the major strategy for treatment.