CAJ | 학술논문

目的：探讨超纯水对维持性血液透析患者氧化应激和炎症水平的影响。方法选择我院2010年1月～2012年10月维持性血液透析患者32例，检测使用超纯水前、后6个月和12个月时各项氧化应激和炎症水平指标的改变。结果使用超纯水后6个月和12个月，所有患者AOPP、MDA和MPO水平均显著下降，GSH-Px水平显著升高，差异均具有统计学意义（P均＜0.05）；所有患者CRP、新喋呤、TNF-α和IL-6水平均显著下降，A1b水平显著升高，差异均具有统计学意义（P均＜0.05）。结论使用超纯水维持性血液透析患者的氧化应激和炎症水平均显著降低。
목적：탐토초순수대유지성혈액투석환자양화응격화염증수평적영향。방법선택아원2010년1월～2012년10월유지성혈액투석환자32례，검측사용초순수전、후6개월화12개월시각항양화응격화염증수평지표적개변。결과사용초순수후6개월화12개월，소유환자AOPP、MDA화MPO수평균현저하강，GSH-Px수평현저승고，차이균구유통계학의의（P균＜0.05）；소유환자CRP、신첩령、TNF-α화IL-6수평균현저하강，A1b수평현저승고，차이균구유통계학의의（P균＜0.05）。결론사용초순수유지성혈액투석환자적양화응격화염증수평균현저강저。
Objective To explore the ultrapure water level of oxidative stress and inflammation in patients with maintenance hemodialysis. Methods Patients with maintenance hemodialysis in weifang people's hospital were selected between January 2010 and October 2012, detection of ultrapure water use before, after 6 months and 12 months when changes in the level of oxidative stress and inflammation indexes.Results Using ultrapure water after 6 months and 12 months, the level of AOPP, MDA, MPO in all patients were significantly decline, GSH-Px levels increased significantly, the differences were statistically significant (P<0.05), all patients with CRP, Neopterin, TNF-α and IL - 6 levels were significantly decline, A1b levels increased signiifcantly, the differences were statistically signiifcant (P<0.05). Conclusion Using ultrapure water maintenance hemodialysis patients of oxidative stress and inlfammation levels were signiifcantly reduced.