CAJ | 학술논문

目的：探讨神经导航辅助显微镜下经蝶切除非侵袭性垂体瘤的手术效果。方法回顾性分析2012年1月~2014年1月我院显微镜下经蝶手术治疗72例非侵袭性垂体瘤的临床资料。结果所有患者均顺利完成手术,65例全切除,4例大部切除,3例部分切除,7例次全切患者均给予伽马刀放射治疗,泌乳素术后仍高者给予溴隐亭治疗。随访6个月~3年,术后头痛缓解率89.2%,视力障碍缓解率68.6%,内分泌功能紊乱缓解率57.6%。5例术后出现脑脊液鼻漏,再次修补后治愈,8例出现一过性尿崩症,给予对症处理后好转,1例部分切除者1.5年后向鞍上及鞍旁进展,开颅再次手术。结论对于非侵袭性垂体瘤来说,显微镜下经蝶入路安全、操作方便,手术效果与神经内镜下经单鼻孔蝶窦入路相比无明显差异。
목적：탐토신경도항보조현미경하경접절제비침습성수체류적수술효과。방법회고성분석2012년1월~2014년1월아원현미경하경접수술치료72례비침습성수체류적림상자료。결과소유환자균순리완성수술,65례전절제,4례대부절제,3례부분절제,7례차전절환자균급여가마도방사치료,비유소술후잉고자급여추은정치료。수방6개월~3년,술후두통완해솔89.2%,시력장애완해솔68.6%,내분비공능문란완해솔57.6%。5례술후출현뇌척액비루,재차수보후치유,8례출현일과성뇨붕증,급여대증처리후호전,1례부분절제자1.5년후향안상급안방진전,개로재차수술。결론대우비침습성수체류래설,현미경하경접입로안전、조작방편,수술효과여신경내경하경단비공접두입로상비무명현차이。
Objective To investigate the effect of neuronavigation assisted microscopic transsphenoidal resection of non-invasived pituitary tumor. Methods Retrospective analysis of clinical data of 72 cases of transsphenoidal operation for non-invasived pituitary tumor from January 2012 to January 2014. Results All patients were successfully completed the surgery, total resection in 65 cases, subtotal resection in 4 cases, partial resection in 3 cases, 7 cases in subtotal resection were treated with gamma knife radiotherapy after operation, hyperprolactin were given bromocriptine treatment after surgery. Patients were followed up for 6 months to 3 years, the remission rate was 89.2% in the postoperative headache, visual disorder remission rate 68.6%, endocrine disorders and the remission rate was 57.6%. 5 cases of post-operative cerebrospinal fluid rhinorrhea underwent repair, 8 cases had diabetes insipidus, 1 case of partial resection progressed to suprasellar and parasellar after 1.5 years, underwent craniotomy operation again. Conclusion For non-in-vasived pituitary tumor, microscopic transsphenoidal sugery is safe, convenient, and has no significant difference com-pared with the effect of endoscopic endonasal transsphenoidal approach.