CAJ | 학술논문

目的：：探讨慢性肾脏病(CKD)患者合并睡眠呼吸暂停低通气综合征(SAHS)对CKD患者心血管疾病(CVD)发病情况的影响。方法：调查92例CKD患者合并SAHS的情况，并分析CKD病情严重程度与SAHS患病率的关系；采用Logistic回归分析法分析CKD合并SAHS时对其CVD发病情况的影响。结果：92例CKD患者合并SAHS的患病率为83.70%(77/92)，以中枢性睡眠呼吸暂停(CSA)为主(49.35%，38/77)；终末期肾脏病患者合并SAHS的患病率明显高于非终末期肾脏病患者(P＜0.05)。Logistic回归分析显示，SAHS是CKD患者并发CVD的预测危险因子(OR=9.41，95% CI：2.16-41.03)；CKD合并SAHS患者CVD患病率明显高于CKD未合并SAHS者(P＜0.05)。结论：CKD患者容易合并SAHS，且以CSA为主；同时，SAHS可以增加CKD患者并发CVD的风险。
목적：：탐토만성신장병(CKD)환자합병수면호흡잠정저통기종합정(SAHS)대CKD환자심혈관질병(CVD)발병정황적영향。방법：조사92례CKD환자합병SAHS적정황，병분석CKD병정엄중정도여SAHS환병솔적관계；채용Logistic회귀분석법분석CKD합병SAHS시대기CVD발병정황적영향。결과：92례CKD환자합병SAHS적환병솔위83.70%(77/92)，이중추성수면호흡잠정(CSA)위주(49.35%，38/77)；종말기신장병환자합병SAHS적환병솔명현고우비종말기신장병환자(P＜0.05)。Logistic회귀분석현시，SAHS시CKD환자병발CVD적예측위험인자(OR=9.41，95% CI：2.16-41.03)；CKD합병SAHS환자CVD환병솔명현고우CKD미합병SAHS자(P＜0.05)。결론：CKD환자용역합병SAHS，차이CSA위주；동시，SAHS가이증가CKD환자병발CVD적풍험。
Objective:To study the influences of chronic kidney disease (CKD) combined sleep apnea-hypopnea syndrome (SAHS) on cardiovascular disease (CAD) incidence of CDK patients.Methods:92 cases of CKD patients combined with SAHS were investigated, and analyzed the relationships between CKD severity and SAHS incidence, as well as inlfuences of CKD combined SAHS on CVD incidence by Logistic regression analysis.Results:The case rate of CKD combined SAHS was 83.70% in 92 CKD patients (77/92), and the type of SAHS was mainly central sleep apnea (49.35%, 38/77). The case rate of end-stage kidney disease combined SAHS was obviously higher than non end-stage kidney disease combined SAHS (P<0.05). Logistic regression analysis showed that SAHS was a risk factor for CKD patients complicated with CVD (OR=9.41, 95% CI: 2.16-41.03); The case rate of CVD in CKD patients combined with SAHS was obviously higher than CKD patients not combined with SAHS (P<0.05).Conclusions:The case rate of CKD combined SAHS is fairly higher, and the type of SAHS is mainly central sleep apnea. Meanwhile, SAHS can increase the risk of CKD patients with CVD.