CAJ | 학술논문

目的：观察胺碘酮用于治疗心力衰竭合并心律失常的临床疗效。方法搜集本院心内科2014～2015年1月收治的心力衰竭合并心律失常患者43例，根据用药的不同分为甲、乙两组，甲组使用胺碘酮，乙组使用稳心颗粒，对比并研究两组的最终疗效。结果（1）两组临床疗效对比，甲组患者的治疗好转率91.3%（21/23）高于乙组80.0%（16/20）， P＜0.05；（2）治疗后两组患者的心功能指标较治疗前均有所改善，且甲组的变化更显著，P＜0.05；（3）两组比较，甲组不良反应的发生率8.7%低于乙组20.0%，P＜0.05。结论胺碘酮用于治疗心力衰竭合并心律失常的临床疗效显著，可以有效改善患者的心功能，提高心肌肌力，临床应用价值高。
목적：관찰알전동용우치료심력쇠갈합병심률실상적림상료효。방법수집본원심내과2014～2015년1월수치적심력쇠갈합병심률실상환자43례，근거용약적불동분위갑、을량조，갑조사용알전동，을조사용은심과립，대비병연구량조적최종료효。결과（1）량조림상료효대비，갑조환자적치료호전솔91.3%（21/23）고우을조80.0%（16/20）， P＜0.05；（2）치료후량조환자적심공능지표교치료전균유소개선，차갑조적변화경현저，P＜0.05；（3）량조비교，갑조불량반응적발생솔8.7%저우을조20.0%，P＜0.05。결론알전동용우치료심력쇠갈합병심률실상적림상료효현저，가이유효개선환자적심공능，제고심기기력，림상응용개치고。
Objective Amiodarone effect in treatment of heart failure complicated with arrhythmia is to be observed.Methods 43 patients of heart failure complicated with arrhythmia were chosen who are treated in cardiology department of hospital from January 2014 to January 2015 and separate them into two groups according to different medication treatment, patients in group A are given amiodarone medication treatment and patients in group B are given metacentric particles medication treatment, and then compare treatment effects between two groups.Results (1) Patients’ treatment improvement rate in group A is 91.3% (21/23), which is much higher than 80.0% (16/20) in group B,P<0.05. (2) patients’heart function in both two groups have been improved after treatment but patients in group A have a much more significant improvement than patients in group B, P<0.05. (3) side-effect incidence in group A is 8.7%, which is much lower than 20.0% in control group,P<0.05.ConclusionAmiodarone medication is of efficacy in treatment of heart failure complicated with arrhythmia, it is conducive to improving patients’ heart function and increasing their myocardial energy, thus, such a medication treatment is of application value.