CAJ | 학술논문

目的：观察大剂量盐酸羟考酮对晚期癌症患者的镇痛效果和不良反应以及对生活质量的影响。方法通过自身对照试验，对应用大剂量盐酸羟考酮治疗的重度癌痛患者，评价疼痛程度、疼痛缓解率、不良反应及生活质量。结果应用大剂量盐酸羟考酮疼痛缓解率为95%。患者生活质量较前提高。结论大剂量盐酸羟考酮值得临床作为第三阶梯止痛药。
목적：관찰대제량염산간고동대만기암증환자적진통효과화불량반응이급대생활질량적영향。방법통과자신대조시험，대응용대제량염산간고동치료적중도암통환자，평개동통정도、동통완해솔、불량반응급생활질량。결과응용대제량염산간고동동통완해솔위95%。환자생활질량교전제고。결론대제량염산간고동치득림상작위제삼계제지통약。
Objective To observe the large dose of oxycodone hydrochloride analgesic effect and adverse reaction in patients with advanced cancer and its influence on quality of life. MethodsThrough contrast test, the application of large dose of oxycodone hydrochloride treatment in patients with severe pain, evaluation of the degree of pain, pain remission rate, adverse reaction and quality of life.Results High doses of oxycodone hydrochloride pain relief rate was 95%. Patients quality of life than before.Conclusion Large dose of oxycodone hydrochloride is wort h clinical application as a third ladder painkillers.