中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2015年
6期
594-597
,共4页
杜文雯%欧阳一非%王惠君%王志宏%苏畅%张继国%张伋%姜红如%张兵
杜文雯%歐暘一非%王惠君%王誌宏%囌暢%張繼國%張伋%薑紅如%張兵
두문문%구양일비%왕혜군%왕지굉%소창%장계국%장급%강홍여%장병
胆固醇%高胆固醇血症%膳食%前瞻性研究
膽固醇%高膽固醇血癥%膳食%前瞻性研究
담고순%고담고순혈증%선식%전첨성연구
Cholesterol%Hypercholesterolemia%Diet%Cohort study
目的 探讨成年居民膳食胆固醇摄入与高胆固醇血症的关系.方法 利用“中国健康与营养调查”数据,本研究中纳入的研究对象为同时参加2004年和2009年2轮调查、且在2009年调查时年龄为25~ 65岁、血样检测和膳食调查数据完整的成年居民,共4 244人.以《中国成人血脂异常防治指南2007》为标准,血清TC≥6.22 mmol/L时,判定为高胆固醇血症.采用非条件logistic回归方法,研究膳食胆固醇摄入与高胆固醇血症的关系.结果 2009年成年居民平均血清TC水平为4.9 mmol/L,高胆固醇血症患病率为9.6%.2004-2009年膳食胆固醇摄入量总体呈大幅增长,尤其是低摄入量组的增幅最大.男性成年居民中2004年膳食胆固醇摄入中低水平者和2009年膳食胆固醇摄入高水平者,高胆固醇血症患病风险增加.女性膳食胆固醇摄入与高胆固醇血症之间未见统计学关联.结论 膳食胆固醇摄入与高胆固醇血症的关系具有性别差异.膳食胆固醇摄入水平升高,可增加男性居民发生高胆固醇血症的危险性.
目的 探討成年居民膳食膽固醇攝入與高膽固醇血癥的關繫.方法 利用“中國健康與營養調查”數據,本研究中納入的研究對象為同時參加2004年和2009年2輪調查、且在2009年調查時年齡為25~ 65歲、血樣檢測和膳食調查數據完整的成年居民,共4 244人.以《中國成人血脂異常防治指南2007》為標準,血清TC≥6.22 mmol/L時,判定為高膽固醇血癥.採用非條件logistic迴歸方法,研究膳食膽固醇攝入與高膽固醇血癥的關繫.結果 2009年成年居民平均血清TC水平為4.9 mmol/L,高膽固醇血癥患病率為9.6%.2004-2009年膳食膽固醇攝入量總體呈大幅增長,尤其是低攝入量組的增幅最大.男性成年居民中2004年膳食膽固醇攝入中低水平者和2009年膳食膽固醇攝入高水平者,高膽固醇血癥患病風險增加.女性膳食膽固醇攝入與高膽固醇血癥之間未見統計學關聯.結論 膳食膽固醇攝入與高膽固醇血癥的關繫具有性彆差異.膳食膽固醇攝入水平升高,可增加男性居民髮生高膽固醇血癥的危險性.
목적 탐토성년거민선식담고순섭입여고담고순혈증적관계.방법 이용“중국건강여영양조사”수거,본연구중납입적연구대상위동시삼가2004년화2009년2륜조사、차재2009년조사시년령위25~ 65세、혈양검측화선식조사수거완정적성년거민,공4 244인.이《중국성인혈지이상방치지남2007》위표준,혈청TC≥6.22 mmol/L시,판정위고담고순혈증.채용비조건logistic회귀방법,연구선식담고순섭입여고담고순혈증적관계.결과 2009년성년거민평균혈청TC수평위4.9 mmol/L,고담고순혈증환병솔위9.6%.2004-2009년선식담고순섭입량총체정대폭증장,우기시저섭입량조적증폭최대.남성성년거민중2004년선식담고순섭입중저수평자화2009년선식담고순섭입고수평자,고담고순혈증환병풍험증가.녀성선식담고순섭입여고담고순혈증지간미견통계학관련.결론 선식담고순섭입여고담고순혈증적관계구유성별차이.선식담고순섭입수평승고,가증가남성거민발생고담고순혈증적위험성.
Objective To explore the association between dietary cholesterol intake and hypercholesterolemia among Chinese adults.Methods In 2009,4 244 adults aged 25-65 years old who participated in both 2004 and 2009 China Health and Nutrition Surveys,and with complete biochemical and dietary data were selected.Hypercholesterolemia were defined as with total cholesterol ≥6.22 mmol/L,according to 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults,Non-conditional logistic regression was used to investigate association between dietary cholesterol intake and hypercholesterolemia.Results The average total cholesterol was 4.9 mmol/L,with prevalence of hypercholesterolemia as 9.6%,in 2009.During 2004 to 2009,dietary cholesterol showed a dramatical increase,with lower intake groups the most.Males who consumed middle or lower dietary cholesterol in 2004 and high intake in 2009 had significantly higher risk of having hypercholesterolemia.However,similar findings did not appear in females.Conclusion The associations between dietary cholesterol intake and hypercholesterolemia were different among Chinese males and females.Dramatic increase of dietary cholesterol intake was related to higher risk of hypercholesterolemia in males.